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However, the first haemoglobin measurement in pregnancy (&lt;18\u00a0weeks' gestation) and the last measurement (&gt;28\u00a0weeks' gestation) were negatively associated with allergic sensitisation (adjusted odds ratio [95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>] per g\/dL 0.91 [0.83 to 0.99] and 0.90 [0.83 to 0.98], respectively). The last haemoglobin measurement was also negatively associated with total IgE (adjusted geometric mean ratio 0.94 [0.88 to 0.99]). Anaemia (haemoglobin &lt;11\u00a0g\/<jats:styled-content style=\"fixed-case\">dL<\/jats:styled-content>) in late pregnancy was negatively associated with forced vital capacity (difference in standard deviation score \u22120.07 [\u22120.13 to \u22120.01]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Clinical Relevance<\/jats:title><jats:p>Lower maternal haemoglobin in pregnancy may be a risk factor for allergic sensitisation, elevated IgE and lower <jats:styled-content style=\"fixed-case\">FVC<\/jats:styled-content> in childhood, which may reflect effects of lower prenatal iron status. However, maternal haemoglobin was not associated with risk of childhood asthma or other allergic disorders.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cea.13034","type":"journal-article","created":{"date-parts":[[2017,9,21]],"date-time":"2017-09-21T14:16:48Z","timestamp":1506003408000},"page":"1615-1624","source":"Crossref","is-referenced-by-count":26,"title":["Haemoglobin concentrations in pregnancy and respiratory and allergic outcomes in childhood: Birth cohort study"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7273-8691","authenticated-orcid":false,"given":"S. O.","family":"Shaheen","sequence":"first","affiliation":[{"name":"Centre for Primary Care and Public Health Barts and The London School of Medicine and Dentistry London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Macdonald\u2010Wallis","sequence":"additional","affiliation":[{"name":"School of Social and Community Medicine University of Bristol Bristol UK"},{"name":"MRC Integrative Epidemiology Unit at the University of Bristol Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. A.","family":"Lawlor","sequence":"additional","affiliation":[{"name":"School of Social and Community Medicine University of Bristol Bristol UK"},{"name":"MRC Integrative Epidemiology Unit at the University of Bristol Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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