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It is well documented that the label of amoxicillin allergy in children is associated with adverse health outcomes such as antibiotic\u2010resistant infections. However, it remains controversial how best to assess children for amoxicillin allergy. While in general it is recommended that skin testing be done prior to drug provocation test in the evaluation of amoxicillin allergy, there is increasing evidence that drug provocation testing could be done in lower risk children without skin testing prior. 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