{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:54:55Z","timestamp":1790506495695,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T00:00:00Z","timestamp":1585612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100011199","name":"FP7 Ideas: European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010587","name":"New Zealand Department of Labour","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001505","name":"Health Research Council of New Zealand","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001505","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Experimental Allergy"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cleaning is associated with an increased risk of asthma symptoms, but few studies have measured functional characteristics of airway disease in cleaners.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>To assess and characterize respiratory symptoms and lung function in professional cleaners, and determine potential risk factors for adverse respiratory outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Symptoms, pre\u2010\/post\u2010bronchodilator lung function, atopy, and cleaning exposures were assessed in 425 cleaners and 281 reference workers in Wellington, New Zealand between 2008 and 2010.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cleaners had an increased risk of current asthma (past 12\u00a0months), defined as: woken by shortness of breath, asthma attack, or asthma medication (OR\u00a0=\u00a01.83, 95% CI\u00a0=\u00a01.18\u20102.85). Despite this, they had similar rates of current wheezing (OR\u00a0=\u00a00.93, 95% CI\u00a0=\u00a00.65\u20101.32) and were less likely to have a doctor diagnosis of asthma ever (OR\u00a0=\u00a00.62, 95% CI\u00a0=\u00a00.42\u20100.92). Cleaners overall had lower lung function (FEV<jats:sub>1<\/jats:sub>, FVC; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.05). Asthma in cleaners was associated with less atopy (OR\u00a0=\u00a00.35, 95% CI\u00a0=\u00a00.13\u20100.90), fewer wheezing attacks (OR\u00a0=\u00a00.40, 95% CI\u00a0=\u00a00.17\u20100.97; &gt;3 vs \u22643 times\/year), and reduced bronchodilator response (6% vs 9% mean FEV<jats:sub>1<\/jats:sub>\u2010%\u2010predicted change, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.05) compared to asthma in reference workers. Cleaning of cafes\/restaurants\/kitchens and using upholstery sprays or liquid multi\u2010use cleaner was associated with symptoms, whilst several exposures were also associated with lung function deficits (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Clinical Relevance<\/jats:title><jats:p>Cleaners are at risk of some asthma\u2010associated symptoms and reduced lung function. However, as it was not strongly associated with wheeze and atopy, and airway obstruction was less reversible, asthma in some cleaners may represent a distinct phenotype.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cea.13597","type":"journal-article","created":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T13:04:05Z","timestamp":1583931845000},"page":"567-576","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Respiratory health in professional cleaners: Symptoms, lung function, and risk factors"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3947-2246","authenticated-orcid":false,"given":"Collin","family":"Brooks","sequence":"first","affiliation":[{"name":"Centre for Public Health Research Massey University Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania","family":"Slater","sequence":"additional","affiliation":[{"name":"Centre for Public Health Research Massey University Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Corbin","sequence":"additional","affiliation":[{"name":"Centre for Public Health Research Massey University Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dave","family":"McLean","sequence":"additional","affiliation":[{"name":"Centre for Public Health Research Massey University Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ridvan Tua","family":"Firestone","sequence":"additional","affiliation":[{"name":"Centre for Public Health Research Massey University Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan\u2010Paul","family":"Zock","sequence":"additional","affiliation":[{"name":"ISGlobal Barcelona Spain"},{"name":"Universitat Pompeu Fabra (UPF) Barcelona Spain"},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP) Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Pearce","sequence":"additional","affiliation":[{"name":"Centre for Public Health Research Massey University Wellington New Zealand"},{"name":"Department of Medical Statistics London School of Hygiene and Tropical Medicine London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen","family":"Douwes","sequence":"additional","affiliation":[{"name":"Centre for Public Health Research Massey University Wellington New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,31]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.2004.015032"},{"key":"e_1_2_7_3_1","unstructured":"BrunEed.The Occupational Safety and Health of Workers. 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