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Originally from South\u2010East Asia, it is considered an invasive species outside its native region. Apart from the ecological and economic implications of its presence, it may cause health problems to humans due to the toxic and allergenic components of its venom. <jats:italic>Vespa velutina nigrithorax<\/jats:italic> has become the most prevalent cause of anaphylaxis due to Hymenoptera venom in some regions of Spain. Although sIgE against both antigen 5 (Vesp v 5) and A1\u2010phospholipase (Vesp v 1) has been detected in these patients, only Vesp v 5 may be considered a dominant allergen. Interestingly, Vesp v 1 appears to be a glycosylated allergen different from A1\u2010phospholipases from other species. Inhibition studies suggest that <jats:italic>Vespula<\/jats:italic> spp venom could behave as primary sensitizer. Besides, changes in sIgE and sIgG4 during <jats:italic>Vespula<\/jats:italic> venom immunotherapy in patients with anaphylaxis due to <jats:italic>V.\u00a0velutina<\/jats:italic> support the use of <jats:italic>Vespula<\/jats:italic> venom extracts to treat these patients. The purpose of this review is to explore the biological behaviour of <jats:italic>V.\u00a0velutina<\/jats:italic> and to summarize the current knowledge of the allergic reactions provoked by this wasp.<\/jats:p>","DOI":"10.1111\/cea.14063","type":"journal-article","created":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T17:40:51Z","timestamp":1637862051000},"page":"489-498","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["The Asian wasp <i>Vespa velutina nigrithorax<\/i>: Entomological and allergological characteristics"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2844-2754","authenticated-orcid":false,"given":"Carmen","family":"Vidal","sequence":"first","affiliation":[{"name":"Allergy Department Complejo Hospitalario Universitario de Santiago Faculty of Medicine University of Santiago de Compostela  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,2]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3406\/bsef.2006.16309"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10340-013-0537-3"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10530-015-0880-9"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3406\/bsef.2006.16372"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3406\/bsef.2009.2741"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocon.2011.04.009"},{"key":"e_1_2_10_8_1","first-page":"193","article-title":"Vespa velutina Lepeletier, 1836 (Hymenoptera: Vespidae), recolectada en la Pen\u00ednsula Ib\u00e9rica","volume":"10","author":"Castro L","year":"2010","journal-title":"Heteropterus Rev Entomol"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-7917.12331"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0185172"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010017\u201006212\u20100"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0094162"},{"key":"e_1_2_10_13_1","first-page":"1","article-title":"The Vespinae of the Indo\u2010Malayan and Papuan areas (Hymenoptera, Vespidae)","volume":"34","author":"Van der Vecht J","year":"1957","journal-title":"Zool Verhandel"},{"key":"e_1_2_10_14_1","first-page":"205","article-title":"Notes on Oriental Vespinae, including some species from China and Japan (Hymenoptera, Vespidae)","volume":"13","author":"Van der Vecht J","year":"1959","journal-title":"Zool Mededel"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aspen.2011.11.004"},{"key":"e_1_2_10_16_1","first-page":"53","article-title":"Vespa velutina Lepeletier, 1836 (Hymenoptera, Vespidae), new species for Portugal","volume":"6","author":"Grosso\u2010Silva JM","year":"2012","journal-title":"Arquivos Entomoloxicos"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.3406\/bsef.2013.2580"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jenvman.2019.109983"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.06.511"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ps.6264"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0075841"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0115943"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00114\u2010005\u20100026\u20105"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/biology10060484"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-76690-2"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0239742"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/insects11100706"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201091541\u20104"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-ento-120710-100708"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/insects10080237"},{"key":"e_1_2_10_31_1","volume-title":"Vespine wasps of the world. 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