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Insights from studying allergic inflammation are revealing previously unappreciated immune mechanisms that confer protective effects against cancer, and evasion pathways that facilitate tumour progression. AllergoOncology sheds light on cancers with poor prognosis, including glioma, where evidence has pointed to allergic triggers that may influence glioma biology through rewiring immune surveillance. Allergic signals point to new biomarkers that may identify groups at higher risk of developing cancer, aid patient stratification and help monitor treatment and clinical outcomes. Allergic mediators such as histamine and IgE levels are emerging biomarkers that can inform cancer risk and lead to clinical interventions that improve outcomes. Emerging cancer immunotherapies, such as tumour antigen\u2010specific IgEs, an evolving therapy class, are and will continue to be inspired by understanding allergic immune response mechanisms. Assays, including the Basophil Activation Test developed for monitoring and managing allergic reactions, are translated to the oncology clinic to evaluate hypersensitivity to anti\u2010cancer therapeutics. Allergy research brings fundamental benefits for oncology through understanding and harnessing allergic and cancer\u2010associated mechanisms in AllergoOncology for patient benefit.<\/jats:p>","DOI":"10.1111\/cea.70234","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T03:12:01Z","timestamp":1770865921000},"page":"344-368","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<scp>AllergoOncology<\/scp>\n                    in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes"],"prefix":"10.1111","volume":"56","author":[{"given":"Jakub","family":"Zydron","sequence":"first","affiliation":[{"name":"St. John's Institute of Dermatology, School of Basic and Medical Biosciences &amp; KHP Centre for Translational Medicine King's College London  Guy\u2019s Hospital London UK"},{"name":"School of Cancer and Pharmaceutical Sciences King's College London, Guy's Hospital  London UK"},{"name":"Randall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anishaa","family":"Balaji","sequence":"additional","affiliation":[{"name":"St. John's Institute of Dermatology, School of Basic and Medical Biosciences &amp; KHP Centre for Translational Medicine King's College London  Guy\u2019s Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3968-9234","authenticated-orcid":false,"given":"Jitesh","family":"Chauhan","sequence":"additional","affiliation":[{"name":"St. John's Institute of Dermatology, School of Basic and Medical Biosciences &amp; KHP Centre for Translational Medicine King's College London  Guy\u2019s Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Alder","sequence":"additional","affiliation":[{"name":"St. John's Institute of Dermatology, School of Basic and Medical Biosciences &amp; KHP Centre for Translational Medicine King's College London  Guy\u2019s Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Chen","sequence":"additional","affiliation":[{"name":"St. John's Institute of Dermatology, School of Basic and Medical Biosciences &amp; KHP Centre for Translational Medicine King's College London  Guy\u2019s Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna M. F.","family":"Wiegman","sequence":"additional","affiliation":[{"name":"St. John's Institute of Dermatology, School of Basic and Medical Biosciences &amp; KHP Centre for Translational Medicine King's College London  Guy\u2019s Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelie","family":"Poli","sequence":"additional","affiliation":[{"name":"Neuro\u2010Immunology Group, Department of Cancer Research Luxembourg Institute of Health  Luxembourg Luxembourg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Jack\u00f3w\u2010Malinowska","sequence":"additional","affiliation":[{"name":"St. John's Institute of Dermatology, School of Basic and Medical Biosciences &amp; KHP Centre for Translational Medicine King's College London  Guy\u2019s Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Cheeseman","sequence":"additional","affiliation":[{"name":"Ludger Ltd., Culham Campus  Abingdon Oxfordshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel I. 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