{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T00:26:58Z","timestamp":1793665618579,"version":"4.5.1"},"reference-count":37,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Experimental Allergy"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Australia has one of the highest rates of food allergy, anaphylaxis hospital admissions and anaphylaxis fatalities worldwide. These trends and sustained advocacy prompted a 2019 Parliamentary Inquiry into Allergies and Anaphylaxis. Among 250 submissions, the Centre for Food Allergy Research called for a national research\u2010coordinating centre and comprehensive allergy research funding. In response to the inquiry, the Australian Government funded the National Allergy Centre of Excellence (NACE) in 2022, and its partner organisation, the National Allergy Council (NAC), to improve health, save lives and reduce the national burden of allergic disease. Here we describe the establishment and early impacts of the NACE. The NACE was established to build critical national research infrastructure and collaboration to transform consumer\u2010centred allergy care. Four interconnected Pillars underpin the plan of action: (1) Transforming Allergy Care, codesigning national trials and embedded clinical research to address knowledge and practice gaps; (2) BioRepository and Discovery, developing Australia's first national Allergy BioRepository (ALBI) to support data\u2010driven discovery; (3) Evidence and Translation, providing living evidence surveillance and synthesis to accelerate translation into policy and practice; and (4) Training and Innovation, building workforce capacity through postgraduate scholarships and fellowships. In just 3\u2009years, the NACE has become a global exemplar, secured further funding and demonstrated excellence in high\u2010impact research, rapid translation into policy and practice, and improved outcomes for people living with allergic disease. The NACE has united over 500 drug, food, insect and respiratory allergy experts. Over 1500 individuals with allergies are enrolled in five research programs initiated in clinical care, including more than 500 families in a national, standardised peanut oral immunotherapy program (ADAPT) and NACE\u2010led evaluation study. The ALBI design and build are well\u2010advanced, and over 5000 academic articles have been assessed through Australia's first drug and food allergy living evidence collections, underpinning clinical guidelines, public health programs and resources. The NACE has been recognised as an European Academy of Allergy and Clinical Immunology\u00a0Advanced Research Centre and a World Allergy Organisation Center of Excellence. In December 2025, the NACE\u2010NAC partnership secured further Federal Government funding to continue driving national impact.<\/jats:p>","DOI":"10.1111\/cea.70392","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T10:27:22Z","timestamp":1785493642000},"page":"1385-1396","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The National Allergy Centre of Excellence\u2013Addressing Australia's Allergy Burden"],"prefix":"10.1111","volume":"56","author":[{"given":"A.","family":"Young","sequence":"first","affiliation":[{"name":"Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Centre for Food Allergy Research  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. J.","family":"Koplin","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Centre for Food Allergy Research  Parkville Victoria Australia"},{"name":"The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. E.","family":"Campbell","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Centre for Food Allergy Research  Parkville Victoria Australia"},{"name":"The Children's Hospital at Westmead  Westmead New South Wales Australia"},{"name":"The University of Sydney  Camperdown New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. M.","family":"Davies","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Edmund","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Centre for Food Allergy Research  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Jamieson","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7045-2040","authenticated-orcid":false,"given":"C. J.","family":"Hornung","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Centre for Food Allergy Research  Parkville Victoria Australia"},{"name":"The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"O'Farrell","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"West","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Kayes","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. A.","family":"Gray","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. L.","family":"Peters","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute  Parkville Victoria Australia"},{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Centre for Food Allergy Research  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Gamble","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Gwynne","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"The University of New South Wales  Randwick New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Lee","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Alfred Health  Prahran Victoria Australia"},{"name":"Austin Health  Heidelberg Victoria Australia"},{"name":"Monash University  Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Lucas","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Sir Charles Gairdner Hospital  Nedlands Western Australia Australia"},{"name":"Perth Children's Hospital  Nedlands Western Australia Australia"},{"name":"The University of Western Australia  Crawley Western Australia Australia"},{"name":"National Allergy Council  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. H.","family":"Katelaris","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Western Sydney University  Campbelltown New South Wales Australia"},{"name":"Campbelltown Hospital  Campbelltown New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7896-2697","authenticated-orcid":false,"given":"M. D.","family":"O'Sullivan","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Centre for Food Allergy Research  Parkville Victoria Australia"},{"name":"Perth Children's Hospital  Nedlands Western Australia Australia"},{"name":"Australasian Society of Allergy and Clinical Immunology  Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. J.","family":"Palmer","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Centre for Food Allergy Research  Parkville Victoria Australia"},{"name":"The University of Western Australia  Crawley Western Australia Australia"},{"name":"The Kids Research Institute Australia  Nedlands Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5111-6367","authenticated-orcid":false,"given":"J.","family":"Trubiano","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"Austin Health  Heidelberg Victoria Australia"},{"name":"The University of Melbourne  Parkville Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8192-7008","authenticated-orcid":false,"given":"S.","family":"van Nunen","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"The University of Sydney  Camperdown New South Wales Australia"},{"name":"Macquarie University  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. L.","family":"Vale","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"The University of Western Australia  Crawley Western Australia Australia"},{"name":"National Allergy Council  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Wanandy","sequence":"additional","affiliation":[{"name":"National Allergy Centre of Excellence  Parkville Victoria Australia"},{"name":"The Royal Hobart Hospital  Hobart Tasmania Australia"},{"name":"The University of Tasmania  Hobart Tasmania Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5683-996X","authenticated-orcid":false,"given":"K. 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