{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:46:37Z","timestamp":1787013997097,"version":"build-2736575974"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,4,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>We present a review of all previously reported cases of epidermolysis bullosa acquisita (EBA) and inflammatory bowel disease (IBD). We found 42 cases of coincident EBA and IBD in the literature: 35 cases of Crohn disease (CD) and 7 of ulcerative colitis (UC). The clinical and immunopathological features of the cases are described and the demographics collected. In the majority of cases, the diagnosis of IBD predated the development of the skin condition. The association between EBA and IBD was more common for CD than for UC. We discuss the immunopathogenesis of IBD and EBA, and also the link between them, namely type VII collagen.<\/jats:p>","DOI":"10.1111\/ced.12114","type":"journal-article","created":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T01:43:18Z","timestamp":1363830198000},"page":"225-230","source":"Crossref","is-referenced-by-count":48,"title":["Epidermolysis bullosa acquisita and inflammatory bowel disease: a review of the literature"],"prefix":"10.1093","volume":"38","author":[{"given":"H.","family":"Reddy","sequence":"first","affiliation":[{"name":"Department of Dermatology James Cook University Hospital Middlesborough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. R.","family":"Shipman","sequence":"additional","affiliation":[{"name":"Department of Dermatology Worcestershire Royal Hospital Worcester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Wojnarowska","sequence":"additional","affiliation":[{"name":"Department of Dermatology James Cook University Hospital Middlesborough UK"},{"name":"Nuffield Department of Clinical Medicine University of Oxford Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,4,1]]},"reference":[{"key":"2023041918355949600_ced12114-bib-0001","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3109\/08916934.2011.606450","article-title":"Epidermolysis bullosa acquisita: autoimmunity to anchoring fibril collagen","volume":"45","author":"Chen","year":"2012","journal-title":"Autoimmunity"},{"key":"2023041918355949600_ced12114-bib-0002","first-page":"48","article-title":"Incidence and distribution of subepidermal autoimmune bullous skin diseases in three French regions","volume":"131","author":"Bernard","year":"1995","journal-title":"Bullous Dis French Study Group Arch Dermatol"},{"key":"2023041918355949600_ced12114-bib-0003","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1159\/000246282","article-title":"Distribution of HLA class II alleles in Korean patients with epidermolysis bullosa acquisita","volume":"193","author":"Lee","year":"1996","journal-title":"Dermatology"},{"key":"2023041918355949600_ced12114-bib-0004","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/1523-1747.ep12470317","article-title":"Increased frequency of HLA DR2 in patients with autoantibodies to EBA antigen: evidence that the expression of autoimmunity to type VII collagen is HLA class II allele associated","volume":"91","author":"Gammon","year":"1988","journal-title":"J Invest Dermatol"},{"key":"2023041918355949600_ced12114-bib-0005","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1046\/j.1523-1747.2002.01772.x","article-title":"The epidermolysis bullosa acquisita antigen (type VII collagen) is present in human colon, and patients with Crohn's disease have autoantibodies to type VII collagen","volume":"118","author":"Chen","year":"2002","journal-title":"J Invest Dermatol"},{"key":"2023041918355949600_ced12114-bib-0006","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1177\/014107688808100821","article-title":"Epidermolysis bullosa acquisita and total ulcerative colitis","volume":"81","author":"Hughes","year":"1988","journal-title":"J R Soc Med"},{"key":"2023041918355949600_ced12114-bib-0007","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/j.1365-2230.2007.02430.x","article-title":"Epidermolysis bullosa acquisita associated with psoriasis vulgaris","volume":"32","author":"Hoshina","year":"2007","journal-title":"Clin Exp Dermatol"},{"key":"2023041918355949600_ced12114-bib-0008","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/nature06005","article-title":"Unravelling the pathogenesis of inflammatory bowel disease","volume":"448","author":"Xavier","year":"2007","journal-title":"Nature"},{"key":"2023041918355949600_ced12114-bib-0009","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1097\/00054725-200405000-00005","article-title":"Autoimmune disorders and extraintestinal manifestations in first-degree familial and sporadic inflammatory bowel disease: a case-control study","volume":"10","author":"Ricart","year":"2004","journal-title":"Inflamm Bowel Dis"},{"key":"2023041918355949600_ced12114-bib-0010","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1136\/pgmj.2004.031633","article-title":"Important cutaneous manifestations of inflammatory bowel disease","volume":"81","author":"Trost","year":"2005","journal-title":"Postgrad Med J"},{"key":"2023041918355949600_ced12114-bib-0011","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1365-2230.2012.04383.x","article-title":"Association between the subepidermal autoimmune blistering diseases linear IG Disease and the pemphigoid group and the inflammatory bowel disease: two case reports and literature review","volume":"37","author":"Shipman","year":"2012","journal-title":"Clin Exp Dermatol"},{"key":"2023041918355949600_ced12114-bib-0012","first-page":"311","article-title":"Bullous epidermolysis of late appearance and Crohn's ileitis","volume":"76","author":"Dupont","year":"1969","journal-title":"Bull Soc Fr Dermatol Syphiligr"},{"key":"2023041918355949600_ced12114-bib-0013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1001\/archderm.1971.04000130003001","article-title":"Epidermolysis bullosa acquisita. 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