{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T13:35:30Z","timestamp":1784900130818,"version":"3.55.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2022,11,10]],"date-time":"2022-11-10T00:00:00Z","timestamp":1668038400000},"content-version":"vor","delay-in-days":101,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T00:00:00Z","timestamp":1653436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mohs micrographic surgery (MMS) for nonmelanoma skin cancer is often quoted as having an excellent safety profile.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the complication rate of patients undergoing MMS in a large UK Mohs unit and subdivide complication rates into mild\/intermediate and major, and to identify potential risk factors necessitating a clinical intervention.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single-centre, cross-sectional study of 1000 consecutive cases of MMS performed with in-house repair. Notes from the postsurgical dressing clinics were reviewed at Visit 1 (Days 7\u201314) and Visit 2 (approximately Week 6). Based upon the intervention required and effect on cosmetic\/functional outcome, complications were classified as minor, intermediate or major. Logistic regression modelling was used to identify risk factors associated with a complication that needed a clinical intervention (i.e. intermediate or major).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 1000 Mohs surgeries were performed on 803 patients, resulting in 1067 excisions. Complication rates in our cohort were low (minor 3.6%, intermediate 3.1% and major 0.8%) Potential risk factors for developing a complication included skin graft (unadjusted OR = 4.89, 95% CI 1.93\u201312.39; fully adjusted OR = 7.13, 95% CI 2.26\u201322.45) and patients undergoing surgery on the forehead (unadjusted OR = 3.32, 95% CI 0.95\u201311.58; fully adjusted OR = 5.34, 95% CI 1.40\u201320.42). Patients whose wounds were allowed to heal by secondary intention healing (6.8%) exhibited no complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We advocate that patients should be informed during the consent procedure that less than 1 in every 100 patients (0.75%) undergoing MMS will have a serious adverse event (major complication) affecting their cosmetic or functional outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ced.15226","type":"journal-article","created":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T05:53:19Z","timestamp":1651384399000},"page":"1536-1542","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Prevalence of wound complications following Mohs micrographic surgery (MMS): a cross-sectional study of 1000 patients undergoing MMS and wound repair in a UK teaching hospital"],"prefix":"10.1093","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7744-4468","authenticated-orcid":false,"given":"David","family":"Rutkowski","sequence":"first","affiliation":[{"name":"Department of Dermatology Northern Care Alliance NHS Foundation Trust Manchester UK"},{"name":"Centre for Dermatology Research The University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoe","family":"Littlewood","sequence":"additional","affiliation":[{"name":"Department of Dermatology Northern Care Alliance NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah Judith Jean","family":"Touyz","sequence":"additional","affiliation":[{"name":"Department of Dermatology Northern Care Alliance NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas James","family":"Collier","sequence":"additional","affiliation":[{"name":"Department of Dermatology Northern Care Alliance NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Madan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Northern Care Alliance NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harvinder Singh","family":"Ghura","sequence":"additional","affiliation":[{"name":"Department of Dermatology Northern Care Alliance NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1831-074X","authenticated-orcid":false,"given":"Zenas Zee Ngai","family":"Yiu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Northern Care Alliance NHS Foundation Trust Manchester UK"},{"name":"Centre for Dermatology Research The University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Telfer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Northern Care Alliance NHS Foundation Trust Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,8,1]]},"reference":[{"key":"2023041114210843100_","volume-title":"Non-melanoma skin cancer statistics","author":"Cancer Research UK"},{"key":"2023041114210843100_","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1097\/DSS.0000000000000296","article-title":"Consensus for nonmelanoma skin cancer treatment: basal cell carcinoma, including a cost analysis of treatment methods","volume":"41","author":"Kauvar","year":"2015","journal-title":"Dermatol Surg"},{"key":"2023041114210843100_","doi-asserted-by":"crossref","first-page":"3011","DOI":"10.1016\/j.ejca.2014.08.018","article-title":"Surgical excision versus Mohs' micrographic surgery for basal cell carcinoma of the face: a randomised clinical trial with 10 year follow-up","volume":"50","author":"Van Loo","year":"2014","journal-title":"Eur J Cancer"},{"key":"2023041114210843100_","doi-asserted-by":"crossref","first-page":"721","DOI":"10.6061\/clinics\/2015(11)01","article-title":"The importance of superficial basal cell carcinoma in a retrospective study of 139 patients who underwent Mohs micrographic surgery in a Brazilian university hospital","volume":"70","author":"Takata Pontes","year":"2015","journal-title":"Clinics"},{"key":"2023041114210843100_","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1111\/bjd.14843","article-title":"Safety, complications and patients' acceptance of Mohs micrographic surgery under local anaesthesia: results from the U.K. MAPS (Mohs Acceptance and Patient Safety) collaboration group","volume":"176","author":"Hussain","year":"2017","journal-title":"Br J Dermatol"},{"key":"2023041114210843100_","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1001\/archderm.139.2.143","article-title":"A prospective evaluation of the incidence of complications associated with Mohs micrographic surgery","volume":"139","author":"Cook","year":"2003","journal-title":"Arch Dermatol"},{"key":"2023041114210843100_","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1016\/j.jaad.2012.05.041","article-title":"The safety of Mohs surgery: a prospective multicenter cohort study","volume":"67","author":"Merritt","year":"2012","journal-title":"J Am Acad Dermatol"},{"key":"2023041114210843100_","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1111\/ijd.14223","article-title":"Differences of Mohs micrographic surgery in basal cell carcinoma versus squamous cell carcinoma","volume":"57","author":"Delgado Jim\u00e9nez","year":"2018","journal-title":"Int J 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