{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:20:39Z","timestamp":1790011239356,"version":"4.0.1"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T00:00:00Z","timestamp":1673049600000},"content-version":"vor","delay-in-days":37,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T00:00:00Z","timestamp":1666915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Menopause, which usually occurs between the age of 45 and 55 years, is associated with falling oestrogen levels due to ovarian follicle depletion. The impact on the cardiovascular system and bone density are well documented; however, further research required to establish the impact on the skin and hair. In this first part of a four-part review, we examine the effect of menopause on the hair. We performed a literature review on dermatology and hair in menopause. Androgens and oestrogens are involved with regulation of the hair cycle, with a reduction in anagen hairs seen in postmenopausal women. Female pattern hair loss and frontal fibrosing alopecia have both been associated with the perimenopausal and postmenopausal states. It is clear that menopause and the change in hormone levels have an impact on the hair cycle and common hair conditions. However, further research is required, particularly to understand the therapeutic targets and role of hormonal therapy.<\/jats:p>","DOI":"10.1111\/ced.15327","type":"journal-article","created":{"date-parts":[[2022,7,7]],"date-time":"2022-07-07T13:12:56Z","timestamp":1657199576000},"page":"2110-2116","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Menopause, skin and common dermatoses. Part 1: hair disorders"],"prefix":"10.1093","volume":"47","author":[{"given":"Erin","family":"Kamp","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospitals Sussex NHS Foundation Trust Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariha","family":"Ashraf","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospitals Sussex NHS Foundation Trust Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"Musbahi","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospitals Sussex NHS Foundation Trust Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"DeGiovanni","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospitals Sussex NHS Foundation Trust Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"2023010808133776500_ced15327-bib-0001","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1046\/j.1440-0960.2001.00524.x","article-title":"Menopause and the skin","volume":"42","author":"Wines","year":"2001","journal-title":"Australas J Dermatol"},{"key":"2023010808133776500_ced15327-bib-0002","volume-title":"Menopause","author":"National Institute for Health and Care Excellence"},{"key":"2023010808133776500_ced15327-bib-0003","doi-asserted-by":"crossref","first-page":"168","DOI":"10.4103\/0976-7800.145152","article-title":"Dermatosis associated with menopause","volume":"5","author":"Nair","year":"2014","journal-title":"J Mid-life Health"},{"key":"2023010808133776500_ced15327-bib-0004","volume-title":"Early menopause","author":"National Health Service"},{"key":"2023010808133776500_ced15327-bib-0005","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.molmed.2012.12.007","article-title":"Estrogen synthesis and signaling pathways during aging: from periphery to brain","volume":"19","author":"Cui","year":"2013","journal-title":"Trends Mol Med"},{"key":"2023010808133776500_ced15327-bib-0006","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1365-2133.2011.10629.x","article-title":"Hormonal changes in menopause: do they contribute to a \u2018midlife hair crisis\u2019 in women?","volume":"165","author":"Mirmirani","year":"2011","journal-title":"Br J Dermatol"},{"key":"2023010808133776500_ced15327-bib-0007","first-page":"1150","volume-title":"Medical Physiology","author":"Boron","year":"2009"},{"key":"2023010808133776500_ced15327-bib-0008","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21155342","article-title":"Hormonal effects on hair follicles","volume":"21","author":"Grymowicz","year":"2020","journal-title":"Int J Mol Sci"},{"key":"2023010808133776500_ced15327-bib-0009","doi-asserted-by":"crossref","first-page":"371","DOI":"10.2165\/00128071-200304060-00001","article-title":"Skin aging and menopause","volume":"4","author":"Raine-Fenning","year":"2003","journal-title":"Am J Clin Dermatol"},{"key":"2023010808133776500_ced15327-bib-0010","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1684\/ejd.2012.1692","article-title":"Skin academy: hair, skin, hormones and menopause \u2013 current status\/knowledge on the management of hair disorders in menopausal women","volume":"22","author":"Blume-Peytavi","year":"2012","journal-title":"Eur J Dermatol"},{"key":"2023010808133776500_ced15327-bib-0011","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.maturitas.2012.10.020","article-title":"Managing hair loss in midlife women","volume":"74","author":"Mirmirani","year":"2013","journal-title":"Maturitas"},{"key":"2023010808133776500_ced15327-bib-0012","doi-asserted-by":"crossref","first-page":"626","DOI":"10.4103\/0378-6323.116732","article-title":"Female pattern hair loss","volume":"79","author":"Singal","year":"2013","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"2023010808133776500_ced15327-bib-0013","volume-title":"British National Formulary. 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