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Clinicopathological findings in this case support the theory that lacrimal fluid can be a metastatic pathway for tumour cells. Dermatologists should be aware of the possibility that cutaneous eyelid melanoma may involve the nasolacrimal system and should examine it during the perioperative period and in postoperative follow-up.<\/jats:p>","DOI":"10.1111\/ced.15339","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T07:54:26Z","timestamp":1658735666000},"page":"2277-2280","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cutaneous eyelid melanoma with lacrimal sac metastasis: the potential role of lacrimal fluid as a metastatic pathway"],"prefix":"10.1093","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0658-6973","authenticated-orcid":false,"given":"Yoshio","family":"Nakamura","sequence":"first","affiliation":[{"name":"Department of Dermatology Keio University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Tanese","sequence":"additional","affiliation":[{"name":"Department of Dermatology Keio University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaori","family":"Kameyama","sequence":"additional","affiliation":[{"name":"Department of Pathology Keio University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Ota","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Keio University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6594-4534","authenticated-orcid":false,"given":"Takaiyuki","family":"Fusumae","sequence":"additional","affiliation":[{"name":"Department of Dermatology Keio University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikuko","family":"Hirai","sequence":"additional","affiliation":[{"name":"Department of Dermatology Keio University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8847-0063","authenticated-orcid":false,"given":"Keitaro","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Department of Dermatology Keio University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeru","family":"Funakoshi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Keio University School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"2023010808134807700_ced15339-bib-0001","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1136\/bjo.76.6.369","article-title":"Nasal and orbital recurrence of conjunctival melanoma 21 years after exenteration","volume":"76","author":"Paridaens","year":"1992","journal-title":"Br J Ophthalmol"},{"key":"2023010808134807700_ced15339-bib-0002","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1136\/bjo.2009.168823","article-title":"Epistaxis or epiphora as a sign for extension of a conjunctival melanoma. 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