{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:20:36Z","timestamp":1792797636263,"version":"4.5.0"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"},{"start":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T00:00:00Z","timestamp":1666224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"name":"Spanish Fondo de Investigaciones Sanitarias","award":["2014_SGR_603"],"award-info":[{"award-number":["2014_SGR_603"]}]},{"name":"Spanish Fondo de Investigaciones Sanitarias","award":["PI15\/00716"],"award-info":[{"award-number":["PI15\/00716"]}]},{"name":"Spanish Fondo de Investigaciones Sanitarias","award":["PI15\/00956"],"award-info":[{"award-number":["PI15\/00956"]}]},{"DOI":"10.13039\/501100004418","name":"Universit\u00e9 Libre de Bruxelles","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004418","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004418","name":"Vrije Universiteit Brussel","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004418","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Line-field confocal optical coherence tomography (LC-OCT) is a new in vivo emerging technique that provides cellular resolution, allows deep imaging (400 \u03bcm) and produces real-time images in both the horizontal and vertical plane and in three dimensions. No previous description of different subtypes of melanocytic lesions and their correlation with histopathology and reflectance confocal microscopy has been reported.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>To describe the features of melanocytic lesions by LC-OCT and their correlation with histopathology and reflectance confocal microscopy (RCM) findings.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Selected melanocytic benign lesions and melanomas were imaged in vivo with RCM and LC-OCT at the Fundaci\u00f3n Hospital Clinic (Barcelona, Spain). A minimum area of 4 \u00d7 4 mm (block image) at four depths (stratum granulosum, suprabasal, layer dermoepidermal junction and upper dermis) were acquired with RCM and a minimum of three cubes with LC-OCT. Horizontal, vertical sections and three-dimensional (3D) cubes of LC-OCT were matched with RCM (Vivablock two-dimensional composite mosaic) and histopathology, with ~5 \u03bcm lateral resolution accuracy (the same cell nuclei were measured in X, Y and Z) and evaluated by three observers experienced in using RCM and histopathology.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In total, 12 melanocytic tumours (2 in situ melanomas, 2 invasive melanomas, 4 atypical naevi, 2 intradermal naevi, 1 compound naevus and 1 junctional naevus) were included. High correlation with 5 \u03bcm accuracy between RCM and LC-OCT was observed for each tumour. The 3D images of melanocytic lesions were obtained with cellular resolution and correlated with both RCM and histopathology, allowing an understanding of the architecture and precise correlation at the cellular level with RCM. Similarities between LC-OCT and RCM for the described diagnostic features and architecture (nests of melanocytic cells, ringed and meshwork pattern, and cellular details of tumour cells as dendritic and pagetoid cells) were confirmed. The main advantage of diagnosis by RCM fixed probe was the ability to produce larger scans of the lesion using mosaicing compared with an LC-OCT handheld probe.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>LC-OCT allows the architectural and cellular description of different types of melanocytic lesions. LC-OCT showed high correlation with histopathology (vertical sections) and RCM (horizontal sections) in melanocytic lesions. Diagnostic criteria for RCM were similar to those for LC-OCT.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1111\/ced.15383","type":"journal-article","created":{"date-parts":[[2022,8,21]],"date-time":"2022-08-21T09:36:54Z","timestamp":1661074614000},"page":"2222-2233","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Morphological evaluation of melanocytic lesions with three-dimensional line-field confocal optical coherence tomography: correlation with histopathology and reflectance confocal microscopy. A pilot study"],"prefix":"10.1093","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6959-7250","authenticated-orcid":false,"given":"Javiera","family":"Perez-Anker","sequence":"first","affiliation":[{"name":"Fundaci\u00f3n Hospital Clinic Barcelona Spain"},{"name":"Melanoma Unit, Department of Dermatology Hospital Cl\u00ednic de Barcelona, IDIBAPS, Universitat de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1337-9745","authenticated-orcid":false,"given":"Susana","family":"Puig","sequence":"additional","affiliation":[{"name":"Melanoma Unit, Department of Dermatology Hospital Cl\u00ednic de Barcelona, IDIBAPS, Universitat de Barcelona Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Raras (CIBERER) Instituto de Salud Carlos III Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3460-0384","authenticated-orcid":false,"given":"Llucia","family":"Alos","sequence":"additional","affiliation":[{"name":"Department of Pathology Hospital Cl\u00ednic de Barcelona, Universitat de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4156-1587","authenticated-orcid":false,"given":"Adriana","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Pathology Hospital Cl\u00ednic de Barcelona, Universitat de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Alejo","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Hospital Clinic Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4009-0659","authenticated-orcid":false,"given":"Elisa","family":"Cinotti","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medical, Surgical and Neurological Sciences University of Siena Siena Italy"},{"name":"Groupe d'Imagerie Cutan\u00e9e Non Invasive (GICNI) of the Soci\u00e9t\u00e9 Fran\u00e7aise de Dermatologie; (SFD) Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1570-7856","authenticated-orcid":false,"given":"Carmen","family":"Orte Cano","sequence":"additional","affiliation":[{"name":"Department of Dermatology H\u00f4pital Erasme, Universit\u00e9 Libre de Bruxelles Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6691-4310","authenticated-orcid":false,"given":"Linda","family":"Tognetti","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medical, Surgical and Neurological Sciences University of Siena Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clement","family":"Lenoir","sequence":"additional","affiliation":[{"name":"Department of Dermatology H\u00f4pital Erasme, Universit\u00e9 Libre de Bruxelles Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jilliana","family":"Monnier","sequence":"additional","affiliation":[{"name":"Dermatology Department AP-HM, Aix-Marseille University Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Machuca","sequence":"additional","affiliation":[{"name":"Department of Bioengineering Universitat Internacional de Catalunya Sant Cugat del Vall\u00e8s Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Castillo","sequence":"additional","affiliation":[{"name":"Department of Pathology Hospital Cl\u00ednic de Barcelona, Universitat de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3513-1206","authenticated-orcid":false,"given":"P","family":"Ros\u00e9s-Gibert","sequence":"additional","affiliation":[{"name":"Melanoma Unit, Department of Dermatology Hospital Cl\u00ednic de Barcelona, IDIBAPS, Universitat de Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Rubegni","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medical, Surgical and Neurological Sciences University of Siena Siena Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9266-0342","authenticated-orcid":false,"given":"Mariano","family":"Suppa","sequence":"additional","affiliation":[{"name":"Groupe d'Imagerie Cutan\u00e9e Non Invasive (GICNI) of the Soci\u00e9t\u00e9 Fran\u00e7aise de Dermatologie; (SFD) Paris France"},{"name":"Department of Dermatology H\u00f4pital Erasme, Universit\u00e9 Libre de Bruxelles Brussels Belgium"},{"name":"Department of Dermatology Institut Jules Bordet, Universit\u00e9 Libre de Bruxelles Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Luc","family":"Perrot","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital of Saint-Etienne Saint-Etienne France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronique","family":"del Marmol","sequence":"additional","affiliation":[{"name":"Department of Dermatology H\u00f4pital Erasme, Universit\u00e9 Libre de Bruxelles Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6998-914X","authenticated-orcid":false,"given":"Josep","family":"Malvehy","sequence":"additional","affiliation":[{"name":"Melanoma Unit, Department of Dermatology Hospital Cl\u00ednic de Barcelona, IDIBAPS, Universitat de Barcelona Barcelona Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Raras (CIBERER) Instituto de Salud Carlos III Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"2023060913385303900_ced15383-bib-0001","doi-asserted-by":"crossref","first-page":"33534","DOI":"10.1364\/OE.26.033534","article-title":"Line-field confocal time-domain optical coherence tomography with dynamic focusing","volume":"26","author":"Barut","year":"2018","journal-title":"Opt Express"},{"key":"2023060913385303900_ced15383-bib-0002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1117\/1.JBO.23.10.106007","article-title":"Line-field confocal optical coherence tomography for high-resolution noninvasive imaging of skin tumors","volume":"23","author":"Dubois","year":"2018","journal-title":"J Biomed Opt"},{"key":"2023060913385303900_ced15383-bib-0003","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1364\/BOE.10.000694","article-title":"Simultaneous dual-band line-field confocal optical coherence tomography: application to skin imaging","volume":"10","author":"Dubois","year":"2019","journal-title":"Biomed Opt Express"},{"key":"2023060913385303900_ced15383-bib-0004","first-page":"e509","article-title":"Line-field confocal optical coherence tomography of sebaceous hyperplasia: a case series","volume":"35","author":"Lenoir","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2023060913385303900_ced15383-bib-0005","first-page":"e900","article-title":"Line-field confocal optical coherence tomography of actinic keratosis: a case series","volume":"35","author":"Lenoir","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2023060913385303900_ced15383-bib-0006","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1111\/srt.13075","article-title":"P. Line-field confocal optical coherence tomography for non-invasive diagnosis of lichenoid dermatoses of the childhood: a case series","volume":"27","author":"Tognetti","year":"2021","journal-title":"Skin Res Technol"},{"key":"2023060913385303900_ced15383-bib-0007","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1111\/ced.14801","article-title":"Line-field confocal optical coherence tomography for actinic keratosis and squamous cell carcinoma: a descriptive study","volume":"46","author":"Cinotti","year":"2021","journal-title":"Clin Exp Dermatol"},{"key":"2023060913385303900_ced15383-bib-0008","doi-asserted-by":"crossref","DOI":"10.1002\/jbio.202000449","article-title":"Line field confocal optical coherence tomography: an adjunctive tool in the diagnosis of autoimmune bullous diseases","volume":"14","author":"Tognetti","year":"2021","journal-title":"J Biophotonics"},{"key":"2023060913385303900_ced15383-bib-0009","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1111\/jdv.17078","article-title":"Line-field confocal optical coherence tomography of basal cell carcinoma: a descriptive study","volume":"35","author":"Suppa","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2023060913385303900_ced15383-bib-0010","doi-asserted-by":"crossref","first-page":"2914","DOI":"10.1111\/jdv.16857","article-title":"In vivo characterization of healthy human skin with a novel, non-invasive imaging technique: line-field confocal optical coherence tomography","volume":"34","author":"Monnier","year":"2020","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2023060913385303900_ced15383-bib-0011","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1111\/srt.12882","article-title":"New findings in non-invasive imaging of aquagenic keratoderma: line-field optical coherence tomography, dermoscopy and reflectance confocal microscopy","volume":"26","author":"Tognetti","year":"2020","journal-title":"Skin Res Technol"},{"key":"2023060913385303900_ced15383-bib-0012","article-title":"Delayed tattoo reaction from red dye with overlapping clinicopathological features: examination with high-frequency ultrasound and line-field optical coherence tomography","volume":"10","author":"Tognetti","year":"2020","journal-title":"Dermatol Pract Concept"},{"key":"2023060913385303900_ced15383-bib-0013","doi-asserted-by":"crossref","first-page":"206","DOI":"10.4103\/ijdvl.IJDVL_546_19","article-title":"Examination of circumscribed palmar hypokeratosis with line-field confocal optical coherence tomography: dermoscopic, ultrasonographic and histopathologic correlates","volume":"86","author":"Tognetti","year":"2020","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"2023060913385303900_ced15383-bib-0014","doi-asserted-by":"crossref","first-page":"e404","DOI":"10.1111\/jdv.17182","article-title":"Line-field confocal optical coherence tomography: a novel, non-invasive imaging technique for a rapid, in-vivo diagnosis of herpes infection of the skin","volume":"35","author":"Lacarrubba","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2023060913385303900_ced15383-bib-0015","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.jaad.2004.06.028","article-title":"Sensitivity and specificity of reflectance-mode confocal microscopy for in vivo diagnosis of basal cell carcinoma: a multicenter study","volume":"51","author":"Nori","year":"2004","journal-title":"J Am Acad Dermatol"},{"key":"2023060913385303900_ced15383-bib-0016","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.1038\/sj.jid.5700993","article-title":"The impact of in vivo reflectance confocal microscopy for the diagnostic accuracy of melanoma and equivocal melanocytic lesions","volume":"127","author":"Pellacani","year":"2007","journal-title":"J Invest Dermatol"},{"key":"2023060913385303900_ced15383-bib-0017","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1001\/archderm.143.7.883","article-title":"Dendritic cells in pigmented basal cell carcinoma: a relevant finding by reflectance-mode confocal microscopy","volume":"143","author":"Segura","year":"2007","journal-title":"Arch Dermatol"},{"key":"2023060913385303900_ced15383-bib-0018","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.jaad.2007.05.044","article-title":"In vivo reflectance confocal microscopy imaging of melanocytic skin lesions: consensus terminology glossary and illustrative images","volume":"57","author":"Scope","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"2023060913385303900_ced15383-bib-0019","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1038\/jid.2012.172","article-title":"In vivo confocal microscopy for diagnosis of melanoma and basal cell carcinoma using a two-step method: analysis of 710 consecutive clinically equivocal cases","volume":"132","author":"Guitera","year":"2012","journal-title":"J Invest Dermatol"},{"key":"2023060913385303900_ced15383-bib-0020","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1111\/bjd.12678","article-title":"Impact of in vivo reflectance confocal microscopy on the number needed to treat melanoma in doubtful lesions","volume":"170","author":"Alarcon","year":"2014","journal-title":"Br J Dermatol"},{"key":"2023060913385303900_ced15383-bib-0021","first-page":"547","article-title":"Update on the use of confocal microscopy in melanoma and non-melanoma skin cancer","volume":"150","author":"Guida","year":"2015","journal-title":"G Ital Dermatol Venereol"},{"key":"2023060913385303900_ced15383-bib-0022","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/bjd.13546","article-title":"Reflectance confocal microscopy correlates of dermoscopic patterns of facial lesions help to discriminate lentigo maligna from pigmented nonmelanocytic macules","volume":"173","author":"De Carvalho","year":"2015","journal-title":"Br J Dermatol"},{"key":"2023060913385303900_ced15383-bib-0023","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.jaad.2019.05.101","article-title":"Improvement of diagnostic confidence and management of equivocal skin lesions by integration of reflectance confocal microscopy in daily practice: prospective study in 2 referral skin cancer centers","volume":"83","author":"Y\u00e9lamos","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"2023060913385303900_ced15383-bib-0024","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00403-015-1608-5","article-title":"In vivo assessment of optical properties of melanocytic skin lesions and differentiation of melanoma from non-malignant lesions by high-definition optical coherence tomography","volume":"308","author":"Boone","year":"2016","journal-title":"Arch Dermatol Res"},{"key":"2023060913385303900_ced15383-bib-0025","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.det.2017.06.008","article-title":"Optical coherence tomography in the diagnosis of skin cancer","volume":"35","author":"Levine","year":"2017","journal-title":"Dermatol Clin"},{"key":"2023060913385303900_ced15383-bib-0026","first-page":"22","article-title":"Dermoscopy, confocal microscopy and other non-invasive tools for the diagnosis of non-melanoma skin cancers and other skin conditions","volume":"97","author":"Malvehy","year":"2017","journal-title":"Acta Derm Venereol"},{"key":"2023060913385303900_ced15383-bib-0027","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1364\/BOE.10.000694","article-title":"Simultaneous dual-band line-field confocal optical coherence tomography: application to skin imaging","volume":"10","author":"Davis","year":"2019","journal-title":"Biomed Opt Express"},{"key":"2023060913385303900_ced15383-bib-0028","doi-asserted-by":"crossref","first-page":"2","DOI":"10.12788\/j.sder.2016.001","article-title":"Current state of imaging in dermatology","volume":"35","author":"Hibler","year":"2016","journal-title":"Semin Cutan Med and Surg"},{"key":"2023060913385303900_ced15383-bib-0029","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.jaad.2019.10.028","article-title":"Presurgical evaluation of basal cell carcinoma using combined reflectance confocal microscopy-optical coherence tomography: a prospective study","volume":"82","author":"Aleissa","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"2023060913385303900_ced15383-bib-0030","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00403-013-1387-9","article-title":"High-definition optical coherence tomography imaging of melanocytic lesions: a pilot study","volume":"306","author":"Boone","year":"2014","journal-title":"Arch Dermatol Res"},{"key":"2023060913385303900_ced15383-bib-0031","doi-asserted-by":"crossref","first-page":"6019","DOI":"10.7150\/jca.47026","article-title":"The potential utility of integrated reflectance confocal microscopy-optical coherence tomography for guiding triage and therapy of basal cell carcinomas","volume":"11","author":"Iftimia","year":"2020","journal-title":"J Cancer"},{"key":"2023060913385303900_ced15383-bib-0032","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/srt.12815","article-title":"Comparison of line-field confocal optical coherence tomography images with histological sections: validation of a new method for in vivo and non-invasive quantification of superficial dermis thickness","volume":"26","author":"Pedrazzani","year":"2020","journal-title":"Skin Res Technol"},{"key":"2023060913385303900_ced15383-bib-0033","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1111\/cup.14067","article-title":"Line-field confocal optical coherence tomography of xanthogranuloma: correlation with vertical and horizontal histopathology","volume":"48","author":"Lacarrubba","year":"2021","journal-title":"J Cutan Pathol"},{"key":"2023060913385303900_ced15383-bib-0034","first-page":"399","article-title":"Line-field confocal optical coherence tomography of benign dermal melanocytic proliferations: a case series","volume":"35","author":"Lenoir","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2023060913385303900_ced15383-bib-0035","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1111\/srt.12949","article-title":"Line-field confocal optical coherence tomography \u2013 practical applications in dermatology and comparison with established imaging methods","volume":"27","author":"Ruini","year":"2021","journal-title":"Skin Res Technol"},{"key":"2023060913385303900_ced15383-bib-0036","doi-asserted-by":"crossref","first-page":"16878","DOI":"10.1038\/s41598-017-17204-5","article-title":"QuPath: open source software for digital pathology image analysis","volume":"7","author":"Bankhead","year":"2017","journal-title":"Sci Rep"},{"key":"2023060913385303900_ced15383-bib-0037","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1001\/archdermatol.2009.228","article-title":"Reflectance confocal microscopy and features of melanocytic lesions: an internet-based study of the reproducibility of terminology","volume":"145","author":"Pellacani","year":"2009","journal-title":"Arch Dermatol"},{"key":"2023060913385303900_ced15383-bib-0038","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1001\/archderm.144.12.1597","article-title":"In vivo confocal microscopic and histopathologic correlations of dermoscopic features in 202 melanocytic lesions","volume":"144","author":"Pellacani","year":"2008","journal-title":"Arch Dermatol"},{"key":"2023060913385303900_ced15383-bib-0039","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1159\/000444706","article-title":"Dynamic optical coherence tomography in dermatology","volume":"232","author":"Ulrich","year":"2016","journal-title":"Dermatology"},{"key":"2023060913385303900_ced15383-bib-0040","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1111\/jdv.17080","article-title":"Dynamic optical coherence tomography shows characteristic alterations of blood vessels in malignant melanoma","volume":"35","author":"Welzel","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2023060913385303900_ced15383-bib-0041","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.3390\/cancers14051140","article-title":"Line-field confocal optical coherence tomography: a new tool for the differentiation between nevi and melanomas?","volume":"14","author":"Schuh","year":"2022","journal-title":"Cancers (Basel)"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ced.15383","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ced.15383","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/47\/12\/2222\/50539420\/ced2222.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/47\/12\/2222\/50539420\/ced2222.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T14:36:54Z","timestamp":1686321414000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/47\/12\/2222\/6966242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":41,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12,1]]},"published-print":{"date-parts":[[2022,12,1]]}},"URL":"https:\/\/doi.org\/10.1111\/ced.15383","relation":{},"ISSN":["1365-2230","0307-6938"],"issn-type":[{"value":"1365-2230","type":"electronic"},{"value":"0307-6938","type":"print"}],"subject":[],"published-other":{"date-parts":[[2022,12,1]]},"published":{"date-parts":[[2022,12,1]]},"assertion":[{"value":"2022-08-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}