{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:24:23Z","timestamp":1792002263988,"version":"4.4.0"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"},{"start":{"date-parts":[[2022,11,20]],"date-time":"2022-11-20T00:00:00Z","timestamp":1668902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 108-2314-B-075-041-MY3"],"award-info":[{"award-number":["MOST 108-2314-B-075-041-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V111C-022"],"award-info":[{"award-number":["V111C-022"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST 108\u20102314\u2010B\u2010075\u2010041\u2010MY3"],"award-info":[{"award-number":["MOST 108\u20102314\u2010B\u2010075\u2010041\u2010MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V111C\u2010022"],"award-info":[{"award-number":["V111C\u2010022"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Sodium\u2013glucose co-transporter 2 inhibitor (SGLT2i) treatment may exert anti-inflammatory effects by modulating the NOD-like receptor family pyrin domain-containing 3 inflammasome and interleukin-17\/23 inflammatory axis, which are both involved in the pathogenesis of psoriasis. However, the relationship between SGLT2i treatment and psoriasis remains unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>To investigate the association between SGLT2i treatment and incident psoriasis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Using the Taiwan National Health Insurance Database for the period 2007\u20132018, we matched 103 745 patients with Type 2 diabetes mellitus (T2DM) receiving SGLT2i with a control group of patients with T2DM who did not use SGLT2i, matching them in a 1 : 2 ratio by age, sex, diabetes duration, insulin use and comorbidities, and evaluating the psoriasis risk in both groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The incident psoriasis risk did not significantly differ between the SGLT2i and control groups [hazard ratio (HR) = 1.24, 95% CI 0.95\u20131.64] after adjustment for potential confounders. Insulin use (HR = 1.65, 95% CI 1.24\u20132.19) and chronic liver disease and cirrhosis (HR = 1.34, 95% CI 1.01\u20131.77) were significantly associated with increased psoriasis risk. A slightly increased psoriasis risk was also detected in certain SGLT2i user subgroups, especially those with renal disease (HR = 2.73, 95% CI 1.45\u20135.13).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>SGLT2i-mediated protective effects in psoriasis could not be established. SGLT2i treatment increased psoriasis risk by 2.7-fold in patients with T2DM exhibiting renal diseases.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1111\/ced.15385","type":"journal-article","created":{"date-parts":[[2022,8,23]],"date-time":"2022-08-23T11:25:57Z","timestamp":1661253957000},"page":"2242-2250","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Association between sodium\u2013glucose co-transporter 2 inhibitors and risk of psoriasis in patients with diabetes mellitus: a nationwide population-based cohort study"],"prefix":"10.1093","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1160-5083","authenticated-orcid":false,"given":"Sheng-Hsiang","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Faculty of Medicine, School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Ying","family":"Wu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan"},{"name":"Institute of Biomedical Informatics National Yang Ming Chiao Tung University Taipei Taiwan"},{"name":"Institute of Public Health and Department of Public Health National Yang Ming Chiao Tung University Taipei Taiwan"},{"name":"Division of Translational Research and Center of Excellence for Cancer Research Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Department of Public Health China Medical University Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Syuan","family":"Lyu","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Informatics National Yang Ming Chiao Tung University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiing-Jenq","family":"Chou","sequence":"additional","affiliation":[{"name":"Institute of Public Health and Department of Public Health National Yang Ming Chiao Tung University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Ting","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Faculty of Medicine, School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan"},{"name":"Department of Dermatology National Yang Ming Chiao Tung University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8393-3900","authenticated-orcid":false,"given":"Chen-Yi","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Dermatology Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Faculty of Medicine, School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan"},{"name":"Institute of Public Health and Department of Public Health National Yang Ming Chiao Tung University Taipei Taiwan"},{"name":"Department of Dermatology National Yang Ming Chiao Tung University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"key":"2023010808134573900_ced15385-bib-0001","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0140-6736(20)32549-6","article-title":"Psoriasis","volume":"397","author":"Griffiths","year":"2021","journal-title":"Lancet"},{"key":"2023010808134573900_ced15385-bib-0002","doi-asserted-by":"crossref","first-page":"19","DOI":"10.4103\/ds.ds_55_20","article-title":"Risk of chronic kidney disease and end-stage renal disease in patients with psoriasis: a systematic review and meta-analysis of cohort studies","volume":"39","author":"Tung","year":"2021","journal-title":"Dermatol Sin"},{"key":"2023010808134573900_ced15385-bib-0003","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jaad.2016.07.064","article-title":"Psoriasis and comorbid diseases: epidemiology","volume":"76","author":"Takeshita","year":"2017","journal-title":"J Am Acad Dermatol"},{"key":"2023010808134573900_ced15385-bib-0004","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.jaad.2013.06.053","article-title":"Meta-analysis of psoriasis, cardiovascular disease, and associated risk factors","volume":"69","author":"Miller","year":"2013","journal-title":"J Am Acad Dermatol"},{"key":"2023010808134573900_ced15385-bib-0005","doi-asserted-by":"crossref","first-page":"166","DOI":"10.4103\/ds.ds_27_20","article-title":"Changes in metabolic parameters in psoriasis patients treated with interleukin-12\/23 blockade (ustekinumab)","volume":"38","author":"Chang","year":"2020","journal-title":"Dermatol Sin"},{"key":"2023010808134573900_ced15385-bib-0006","doi-asserted-by":"crossref","first-page":"81","DOI":"10.4103\/ds.ds_35_19","article-title":"Association of the attachment styles with depression, anxiety, and quality of life in patients with psoriasis","volume":"38","author":"Demirci","year":"2020","journal-title":"Dermatol Sin"},{"key":"2023010808134573900_ced15385-bib-0007","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1007\/s13555-020-00442-3","article-title":"Psoriasis is associated with a high comedication burden: a population based register study","volume":"10","author":"Duvetorp","year":"2020","journal-title":"Dermatol Ther (Heidelb)"},{"key":"2023010808134573900_ced15385-bib-0008","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1111\/bcp.15060","article-title":"Antihypertensive drug use and psoriasis: a systematic review, meta- and network meta-analysis","volume":"88","author":"Song","year":"2022","journal-title":"Br J Clin Pharmacol"},{"key":"2023010808134573900_ced15385-bib-0009","doi-asserted-by":"crossref","first-page":"366","DOI":"10.4103\/ijdvl.IJDVL_428_18","article-title":"The bidirectional association between type 2 diabetes and psoriasis: two retrospective cohort studies","volume":"86","author":"Chiu","year":"2020","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"2023010808134573900_ced15385-bib-0010","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.jaad.2017.10.050","article-title":"Psoriasis and the risk of diabetes: a prospective population-based cohort study","volume":"78","author":"Wan","year":"2018","journal-title":"J Am Acad Dermatol"},{"key":"2023010808134573900_ced15385-bib-0011","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jaad.2014.08.042","article-title":"Association between antidiabetic drugs and psoriasis risk in diabetic patients: results from a nationwide nested case-control study in Taiwan","volume":"72","author":"Wu","year":"2015","journal-title":"J Am Acad Dermatol"},{"key":"2023010808134573900_ced15385-bib-0012","doi-asserted-by":"crossref","DOI":"10.1111\/eci.13377","article-title":"Effects of antidiabetic drugs on psoriasis: a meta-analysis","volume":"51","author":"Chi","year":"2021","journal-title":"Eur J Clin Invest"},{"key":"2023010808134573900_ced15385-bib-0013","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1007\/s00592-020-01533-5","article-title":"Dipeptidyl peptidase-4 inhibitors and the risks of autoimmune diseases in type 2 diabetes mellitus patients in Taiwan: a nationwide population-based cohort study","volume":"57","author":"Chen","year":"2020","journal-title":"Acta Diabetol"},{"key":"2023010808134573900_ced15385-bib-0014","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1161\/CIRCULATIONAHA.116.021887","article-title":"Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications","volume":"134","author":"Heerspink","year":"2016","journal-title":"Circulation"},{"key":"2023010808134573900_ced15385-bib-0015","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ahj.2020.10.064","article-title":"Effect of sodium-glucose cotransporter 2 inhibitors on cardiovascular and kidney outcomes \u2013 systematic review and meta-analysis of randomized placebo-controlled trials","volume":"232","author":"Salah","year":"2021","journal-title":"Am Heart J"},{"key":"2023010808134573900_ced15385-bib-0016","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1038\/s41467-020-15983-6","article-title":"SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease","volume":"11","author":"Kim","year":"2020","journal-title":"Nat Commun"},{"key":"2023010808134573900_ced15385-bib-0017","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/ni.3659","article-title":"Postprandial macrophage-derived IL-1beta stimulates insulin, and both synergistically promote glucose disposal and inflammation","volume":"18","author":"Dror","year":"2017","journal-title":"Nat Immunol"},{"key":"2023010808134573900_ced15385-bib-0018","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/nm.3804","article-title":"The ketone metabolite beta-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease","volume":"21","author":"Youm","year":"2015","journal-title":"Nat Med"},{"key":"2023010808134573900_ced15385-bib-0019","doi-asserted-by":"crossref","first-page":"5898","DOI":"10.3390\/ijms22115898","article-title":"The role of NLRP1, NLRP3, and AIM2 inflammasomes in psoriasis: review","volume":"22","author":"Ciazynska","year":"2021","journal-title":"Int J Mol Sci"},{"key":"2023010808134573900_ced15385-bib-0020","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1001\/jamadermatol.2020.2430","article-title":"Association of sensorineural hearing loss in patients with alopecia areata: a nationwide population-based cohort study","volume":"156","author":"Ma","year":"2020","journal-title":"JAMA Dermatol"},{"key":"2023010808134573900_ced15385-bib-0021","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.jaad.2021.10.045","article-title":"Association between alopecia areata and retinal diseases: a nationwide population-based cohort study","volume":"87","author":"Ting","year":"2022","journal-title":"J Am Acad Dermatol"},{"key":"2023010808134573900_ced15385-bib-0022","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4103\/ds.ds_30_19","article-title":"Is rosacea a risk factor for cancer: a population-based cohort study in Taiwan","volume":"38","author":"Wu","year":"2020","journal-title":"Dermatol Sin"},{"key":"2023010808134573900_ced15385-bib-0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.diabres.2020.108546","article-title":"Association between dipeptidyl peptidase-4 inhibitors and risk of bullous pemphigoid in patients with type 2 diabetes: a population-based cohort study","volume":"171","author":"Wu","year":"2021","journal-title":"Diabetes Res Clin Pract"},{"key":"2023010808134573900_ced15385-bib-0024","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1016\/j.jid.2017.01.036","article-title":"All-cause and cause-specific mortality in patients with psoriasis in Taiwan: a nationwide population-based study","volume":"137","author":"Lee","year":"2017","journal-title":"J Invest Dermatol"},{"key":"2023010808134573900_ced15385-bib-0025","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.jacbts.2020.02.004","article-title":"Mechanisms of cardiovascular benefits of sodium glucose co-transporter 2 (SGLT2) inhibitors: a state-of-the-art review","volume":"5","author":"Lopaschuk","year":"2020","journal-title":"JACC Basic Transl Sci"},{"key":"2023010808134573900_ced15385-bib-0026","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1007\/s00125-019-4859-4","article-title":"Canagliflozin reduces inflammation and fibrosis biomarkers: a potential mechanism of action for beneficial effects of SGLT2 inhibitors in diabetic kidney disease","volume":"62","author":"Heerspink","year":"2019","journal-title":"Diabetologia"},{"key":"2023010808134573900_ced15385-bib-0027","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.3390\/jcm8111814","article-title":"The SGLT2 inhibitor empagliflozin ameliorates the inflammatory profile in type 2 diabetic patients and promotes an antioxidant response in leukocytes","volume":"8","author":"Iannantuoni","year":"2019","journal-title":"J Clin Med"},{"key":"2023010808134573900_ced15385-bib-0028","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1007\/s10741-020-10065-7","article-title":"Beneficial effects on kidney during treatment with sodium-glucose cotransporter 2 inhibitors: proposed role of ketone utilization","volume":"26","author":"Hattori","year":"2021","journal-title":"Heart Fail Rev"},{"key":"2023010808134573900_ced15385-bib-0029","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/s41577-019-0165-0","article-title":"The NLRP3 inflammasome: molecular activation and regulation to therapeutics","volume":"19","author":"Swanson","year":"2019","journal-title":"Nat Rev Immunol"},{"key":"2023010808134573900_ced15385-bib-0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.107492","article-title":"The SGLT2 inhibitor empagliflozin negatively regulates IL-17\/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK\/mTOR\/autophagy pathway","volume":"94","author":"Meng","year":"2021","journal-title":"Int Immunopharmacol"},{"key":"2023010808134573900_ced15385-bib-0031","doi-asserted-by":"crossref","first-page":"199","DOI":"10.4103\/ds.ds_42_20","article-title":"C-reactive protein to albumin ratio: is a new parameter for the disease severity in patients with psoriasis vulgaris?","volume":"38","author":"Kemeriz","year":"2020","journal-title":"Dermatol Sin"},{"key":"2023010808134573900_ced15385-bib-0032","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1600-0625.2011.01261.x","article-title":"The \u2018psoriatic march\u2019: a concept of how severe psoriasis may drive cardiovascular comorbidity","volume":"20","author":"Boehncke","year":"2011","journal-title":"Exp Dermatol"},{"key":"2023010808134573900_ced15385-bib-0033","article-title":"Sodium-glucose co-transporter-2 inhibitor-induced pruritus: itching for answers","volume":"13","author":"Ali","year":"2021","journal-title":"Cureus"},{"key":"2023010808134573900_ced15385-bib-0034","doi-asserted-by":"crossref","first-page":"38","DOI":"10.2174\/1574886311666160405110515","article-title":"Generalized intense pruritus during canagliflozin treatment: is it an adverse drug reaction?","volume":"13","author":"Vasapollo","year":"2018","journal-title":"Curr Drug Saf"},{"key":"2023010808134573900_ced15385-bib-0035","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s13300-020-00950-7","article-title":"A prospective, open-label short-term pilot study on modification of the skin hydration status during treatment with a sodium-glucose cotransporter-2 inhibitor","volume":"12","author":"Tezuka","year":"2021","journal-title":"Diabetes Ther"},{"key":"2023010808134573900_ced15385-bib-0036","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12933-017-0654-z","article-title":"SGLT-2-inhibition with dapagliflozin reduces tissue sodium content: a randomised controlled trial","volume":"17","author":"Karg","year":"2018","journal-title":"Cardiovasc Diabetol"},{"key":"2023010808134573900_ced15385-bib-0037","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.jid.2021.06.013","article-title":"Skin sodium accumulates in psoriasis and reflects disease severity","volume":"142","author":"Maifeld","year":"2022","journal-title":"J Invest Dermatol"},{"key":"2023010808134573900_ced15385-bib-0038","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s40262-015-0264-4","article-title":"Pharmacokinetics, pharmacodynamics and clinical use of SGLT2 inhibitors in patients with type 2 diabetes mellitus and chronic kidney disease","volume":"54","author":"Scheen","year":"2015","journal-title":"Clin Pharmacokinet"},{"key":"2023010808134573900_ced15385-bib-0039","first-page":"517","article-title":"Non-alcoholic fatty liver disease and psoriasis \u2013 is there a shared proinflammatory network?","volume":"19","author":"Heitmann","year":"2021","journal-title":"J Dtsch Dermatol Ges"},{"key":"2023010808134573900_ced15385-bib-0040","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1111\/1346-8138.16129","article-title":"Association between hepatitis C virus infection and subsequent chronic inflammatory skin disease","volume":"48","author":"Ma","year":"2021","journal-title":"J Dermatol"},{"key":"2023010808134573900_ced15385-bib-0041","first-page":"75","article-title":"Psoriasis and alcohol","volume":"9","author":"Svanstrom","year":"2019","journal-title":"Psoriasis (Auckl)"},{"key":"2023010808134573900_ced15385-bib-0042","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/ced.12013","article-title":"Alcohol and psoriasis: sobering thoughts","volume":"38","author":"Adamzik","year":"2013","journal-title":"Clin Exp Dermatol"},{"key":"2023010808134573900_ced15385-bib-0043","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.jaad.2007.11.023","article-title":"Association between use of thiazolidinediones or other oral antidiabetics and psoriasis: a population based case-control study","volume":"58","author":"Brauchli","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"2023010808134573900_ced15385-bib-0044","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s12026-018-9005-8","article-title":"Is there an association between dipeptidyl peptidase-4 inhibitors and autoimmune disease? A population-based study","volume":"66","author":"Kridin","year":"2018","journal-title":"Immunol Res"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ced.15385","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ced.15385","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/47\/12\/2242\/48531079\/ced2242.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/47\/12\/2242\/48531079\/ced2242.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T14:59:00Z","timestamp":1676386740000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/47\/12\/2242\/6966189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,1]]},"references-count":44,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12,1]]},"published-print":{"date-parts":[[2022,12,1]]}},"URL":"https:\/\/doi.org\/10.1111\/ced.15385","relation":{},"ISSN":["1365-2230","0307-6938"],"issn-type":[{"value":"1365-2230","type":"electronic"},{"value":"0307-6938","type":"print"}],"subject":[],"published-other":{"date-parts":[[2022,12,1]]},"published":{"date-parts":[[2022,12,1]]},"assertion":[{"value":"2022-08-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}