{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T17:25:26Z","timestamp":1767374726464,"version":"3.37.3"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T00:00:00Z","timestamp":1637020800000},"content-version":"vor","delay-in-days":480,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,16]]},"abstract":"<jats:title>Summary<\/jats:title>\n               <jats:p>Primary pneumococcal peritonitis is a rare infection that has been described in women but has not been previously linked with immunodeficiency. The complement system plays a central role in immune defence against Streptococcus pneumoniae and, in order to evade complement attack, pneumococci have evolved a large number of mechanisms that limit complement-mediated opsonization and subsequent phagocytosis. We investigated an apparently immunocompetent woman with primary pneumococcal peritonitis and identified a family with deficiency for complement factor I. Primary pneumococcal peritonitis should be considered a possible primary immunodeficiency presentation.<\/jats:p>","DOI":"10.1111\/cei.13490","type":"journal-article","created":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T19:05:06Z","timestamp":1594235106000},"page":"379-383","source":"Crossref","is-referenced-by-count":5,"title":["Primary pneumococcal peritonitis can be the first presentation of a familial complement factor I deficiency1"],"prefix":"10.1093","volume":"202","author":[{"given":"S","family":"Ugrinovic","sequence":"first","affiliation":[{"name":"Department of Immunology, Cambridge University Hospital NHS Trust, Cambridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Firth","sequence":"additional","affiliation":[{"name":"Department of Clinical Genetics, Cambridge University Hospital NHS Trust, Cambridge, 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