{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T22:01:36Z","timestamp":1768514496807,"version":"3.49.0"},"reference-count":76,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,9,4]],"date-time":"2013-09-04T00:00:00Z","timestamp":1378252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>There is increasing interest in fertility and use of assisted reproductive technologies for women with <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>urner syndrome (<jats:styled-content style=\"fixed-case\">TS<\/jats:styled-content>). Current parenting options include adoption, surrogacy, and spontaneous and assisted reproduction. For women with <jats:styled-content style=\"fixed-case\">TS<\/jats:styled-content>, specific risks of pregnancy include higher than usual rates of spontaneous abortion, foetal anomaly, maternal morbidity and mortality. Heterologous fertility assistance using oocytes from related or unrelated donors is an established technique for women with TS. Homologous fertility preservation includes cryopreservation of the patient's own gametes prior to the progressive ovarian atresia known to occur: preserving either mature oocytes or ovarian tissue containing primordial follicles. Mature oocyte cryopreservation requires ovarian stimulation and can be performed only in postpubertal individuals, when few women with TS have viable oocytes. Ovarian tissue cryopreservation, however, can be performed in younger girls prior to ovarian atresia \u2013 over 30 pregnancies have resulted using this technique, however, none in women with <jats:styled-content style=\"fixed-case\">TS<\/jats:styled-content>. We recommend consideration of homologous fertility preservation techniques in children only within specialized centres, with informed consent using protocols approved by a research or clinical ethics board. It is essential that further research is performed to improve maternal and foetal outcomes for women with TS.<\/jats:p>","DOI":"10.1111\/cen.12288","type":"journal-article","created":{"date-parts":[[2013,7,12]],"date-time":"2013-07-12T04:22:58Z","timestamp":1373602978000},"page":"606-614","source":"Crossref","is-referenced-by-count":48,"title":["Fertility in <scp>T<\/scp>urner syndrome"],"prefix":"10.1111","volume":"79","author":[{"given":"Jacqueline K.","family":"Hewitt","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Diabetes Royal Children's Hospital Melbourne Melbourne Vic. Australia"},{"name":"Murdoch Childrens Research Institute Melbourne Vic. Australia"},{"name":"University of Melbourne Melbourne Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmin","family":"Jayasinghe","sequence":"additional","affiliation":[{"name":"University of Melbourne Melbourne Vic. 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