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There are three main settings for such lymphocyte reconstitution: recovery after a bone marrow or haematopoietic stem cell transplant, alemtuzumab treatment and the use of highly active antiretroviral therapy (<jats:styled-content style=\"fixed-case\">HAART<\/jats:styled-content>) for human immunodeficiency virus infection. The available evidence suggests that Graves' disease behaves as normal in most of these cases and should be treated conventionally, but it may follow a more favourable course in those receiving alemtuzumab or <jats:styled-content style=\"fixed-case\">HAART<\/jats:styled-content>. As spontaneous or drug\u2010induced remission may be more likely in these two settings, first\u2010line treatment should usually consist of an antithyroid drug.<\/jats:p>","DOI":"10.1111\/cen.12427","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T11:26:00Z","timestamp":1392636360000},"page":"629-632","source":"Crossref","is-referenced-by-count":43,"title":["Graves' disease following immune reconstitution or immunomodulatory treatment: should we manage it any differently?"],"prefix":"10.1111","volume":"80","author":[{"given":"Anthony P.","family":"Weetman","sequence":"first","affiliation":[{"name":"Department of Human Metabolism Faculty of Medicine Dentistry and Health The Medical School University of Sheffield Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,9]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2013.0241"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2009.07.003"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)02429-0"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318228bec5"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-08-371138"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.081661"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01258.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.85.11.4254"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-0055"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-1949"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.md.0000159082.45703.90"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000006"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2004.14.1097"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0055"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-131-2-199907200-00023"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.51.439"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-08-0944"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcr050"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0618"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.4158\/EP.17.3.456"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1089\/105072503322238809"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0565"},{"key":"e_1_2_5_24_1","first-page":"120","article-title":"Use of Color Doppler Ultrasonography to Measure Thyroid Blood Flow and Differentiate Graves' Disease from Painless Thyroiditis","volume":"2","author":"Hiraiwa T.","year":"2013","journal-title":"European Thyroid Journal"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2002.01553.x"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-2201"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61769-3"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2011.0309"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2013.08.002"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1293.2007.00422.x"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1700955"}],"container-title":["Clinical Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcen.12427","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cen.12427","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T02:05:27Z","timestamp":1696298727000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cen.12427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,9]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["10.1111\/cen.12427"],"URL":"https:\/\/doi.org\/10.1111\/cen.12427","archive":["Portico"],"relation":{},"ISSN":["0300-0664","1365-2265"],"issn-type":[{"value":"0300-0664","type":"print"},{"value":"1365-2265","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,9]]}}}