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An important consideration to guide the assignment of social sex in newborns with ambiguous genitalia is the quality of life (QoL) of these patients in adulthood. The rarity of most <jats:styled-content style=\"fixed-case\">DSD<\/jats:styled-content> conditions makes it difficult to conduct a long\u2010term follow\u2010up of affected patients through adulthood. This review of papers on the QoL of <jats:styled-content style=\"fixed-case\">DSD<\/jats:styled-content> patients evaluated in developing and developed countries by qualitative and quantitative instruments revealed a large spectrum of QoL, ranging from very poor to similar to, or even better than, the normal population. A more adequate QoL was found in patients from tertiary centres, indicating that the medical care of <jats:styled-content style=\"fixed-case\">DSD<\/jats:styled-content> patients should be multidisciplinary and carried out by specialized teams.<\/jats:p>","DOI":"10.1111\/cen.12561","type":"journal-article","created":{"date-parts":[[2014,7,19]],"date-time":"2014-07-19T07:07:39Z","timestamp":1405753659000},"page":"159-164","source":"Crossref","is-referenced-by-count":36,"title":["Quality of life of patients with 46,<scp>XX<\/scp> and 46,<scp>XY<\/scp> disorders of sex development"],"prefix":"10.1111","volume":"82","author":[{"given":"Rita Cassia","family":"Amaral","sequence":"first","affiliation":[{"name":"Unidade de Endocrinologia do Desenvolvimento Laborat\u00f3rio de Horm\u00f4nios e Gen\u00e9tica Molecular LIM\/42 Disciplina de Endocrinologia Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlene","family":"Inacio","sequence":"additional","affiliation":[{"name":"Unidade de Endocrinologia do Desenvolvimento Laborat\u00f3rio de Horm\u00f4nios e Gen\u00e9tica Molecular LIM\/42 Disciplina de Endocrinologia Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinicius N.","family":"Brito","sequence":"additional","affiliation":[{"name":"Unidade de Endocrinologia do Desenvolvimento Laborat\u00f3rio de Horm\u00f4nios e Gen\u00e9tica Molecular LIM\/42 Disciplina de Endocrinologia Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania A. 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