{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T10:10:48Z","timestamp":1790763048281,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,3,9]],"date-time":"2015-03-09T00:00:00Z","timestamp":1425859200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Context<\/jats:title><jats:p>Vitamin D deficiency is widely prevalent throughout the world. Pregnant women, neonates and infants form most vulnerable groups for vitamin D deficiency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>(1) To find prevalence of vitamin D deficiency in pregnant women. (2) To evaluate the effect of supplementation with cholecalciferol in improving vitamin D levels in pregnant women and evaluate its correlation with feto\u2010maternal outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Randomized control trial from years 2010 to 2012.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tertiary care centre, Delhi, India.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>One\u2010hundred and eighty pregnant women. Study population divided randomly into two groups: group A: nonintervention (60 women) and group B: intervention (120 women).<\/jats:p><\/jats:sec><jats:sec><jats:title>Intervention<\/jats:title><jats:p>The intervention group received supplementation of vitamin D in dosages depending upon 25(<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content>)\u2010D levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Risk of maternal complications such as preterm labour, pre\u2010eclampsia and gestational diabetes associated with vitamin D deficiency and risk of low birthweight and poor Apgar score in infants of mothers with vitamin D deficiency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Adjusted serum 25(<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content>)\u2010D concentration was lower in group A as compared to group B (mean 46\u00b711\u00a0\u00b1\u00a074\u00b721\u00a0nmol\/l <jats:italic>vs<\/jats:italic> 80\u00a0\u00b1\u00a051\u00b753\u00a0nmol\/l). Forty\u2010four percent patients in group A and 20\u00b73% patients in group B developed preterm labour\/pre\u2010eclampsia\/gestational diabetes. Newborns of mothers in group A had lower cord blood levels of 25(<jats:styled-content style=\"fixed-case\">OH<\/jats:styled-content>)\u2010D levels as compared to group B (mean 43\u00b711\u00a0\u00b1\u00a081\u00b732\u00a0nmol\/l <jats:italic>vs<\/jats:italic> 56\u00b78\u00a0\u00b1\u00a047\u00b752\u00a0nmol\/l). They also had lower birthweight of mean 2\u00b74\u00a0\u00b1\u00a00\u00b738\u00a0kg as compared to group B 2\u00b76\u00a0\u00b1\u00a00\u00b733\u00a0kg.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Vitamin D supplementation reduces risk of maternal comorbidities and helps improve neonatal outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cen.12751","type":"journal-article","created":{"date-parts":[[2015,2,14]],"date-time":"2015-02-14T07:35:12Z","timestamp":1423899312000},"page":"536-541","source":"Crossref","is-referenced-by-count":164,"title":["Supplementation of vitamin D in pregnancy and its correlation with feto\u2010maternal outcome"],"prefix":"10.1111","volume":"83","author":[{"given":"Aanchal","family":"Sablok","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Vardhman Mahavir Medical College and Safdarjung Hospital New Delhi 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