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However, epidemiological studies exploring the association between <jats:styled-content style=\"fixed-case\">WBV<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> were not available.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Our objective was to evaluate the association between <jats:styled-content style=\"fixed-case\">WBV<\/jats:styled-content> levels and risk of prevalent <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>This was a cross\u2010sectional population\u2010based study performed in Shanghai, China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients<\/jats:title><jats:p>A total of 8673 participants aged 40\u00a0years or older were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">WBV<\/jats:styled-content> was calculated from haematocrit and plasma protein concentration, at a shear rate of 208<jats:sup>\u22121<\/jats:sup>\u00a0s, by a validated equation. <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> was diagnosed by hepatic ultrasound after the exclusion of alcohol abuse and other liver diseases. Insulin resistance (<jats:styled-content style=\"fixed-case\">IR<\/jats:styled-content>) was assessed by homeostasis model assessment (<jats:styled-content style=\"fixed-case\">HOMA<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">IR<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall prevalence of <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> was 30\u00b72% in this population. With the increase of <jats:styled-content style=\"fixed-case\">WBV<\/jats:styled-content> level, participants have larger waist circumference (<jats:styled-content style=\"fixed-case\">WC<\/jats:styled-content>), more severe insulin resistance and the prevalence of <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> increased significantly with elevated <jats:styled-content style=\"fixed-case\">WBV<\/jats:styled-content> quartiles. Compared with those in the lowest quartiles, adults in the highest quartile of <jats:styled-content style=\"fixed-case\">WBV<\/jats:styled-content> levels have higher prevalence of <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> (adjusted odds ratio 1\u00b777, 95% confidence interval [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>] 1\u00b748\u20132\u00b713) and <jats:styled-content style=\"fixed-case\">IR<\/jats:styled-content> (2\u00b772, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 2\u00b726\u20133\u00b727).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Elevated <jats:styled-content style=\"fixed-case\">WBV<\/jats:styled-content> is associated with prevalence of <jats:styled-content style=\"fixed-case\">NAFLD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">IR<\/jats:styled-content> in middle\u2010aged and elderly Chinese population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cen.12776","type":"journal-article","created":{"date-parts":[[2015,3,30]],"date-time":"2015-03-30T13:59:10Z","timestamp":1427723950000},"page":"806-811","source":"Crossref","is-referenced-by-count":14,"title":["Elevated whole blood viscosity is associated with insulin resistance and non\u2010alcoholic fatty liver"],"prefix":"10.1111","volume":"83","author":[{"given":"Hong\u2010yan","family":"Zhao","sequence":"first","affiliation":[{"name":"Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health The National Clinical Research Center for Metabolic Diseases of Ministry of Health Rui\u2010Jin Hospital Shanghai Jiao\u2010Tong University School of Medicine E\u2010Institute of Shanghai Universities Shanghai China"},{"name":"Shanghai Clinical Center for Endocrine and\u00a0Metabolic Diseases Shanghai Institute of Endocrine and Metabolic Diseases Department of Endocrine and Metabolic Diseases Rui\u2010Jin Hospital Shanghai Jiao\u2010Tong University School of\u00a0Medicine Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health The National Clinical Research Center for Metabolic Diseases of Ministry of Health Rui\u2010Jin Hospital Shanghai Jiao\u2010Tong University School of Medicine E\u2010Institute of Shanghai Universities Shanghai China"},{"name":"Shanghai Clinical Center for Endocrine and\u00a0Metabolic Diseases Shanghai Institute of Endocrine and Metabolic Diseases Department of Endocrine and Metabolic Diseases Rui\u2010Jin Hospital Shanghai Jiao\u2010Tong University School of\u00a0Medicine Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Xu","sequence":"additional","affiliation":[{"name":"Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health The National Clinical Research Center for Metabolic Diseases of Ministry of Health Rui\u2010Jin Hospital Shanghai Jiao\u2010Tong University School of Medicine E\u2010Institute of Shanghai Universities Shanghai China"},{"name":"Shanghai Clinical Center for Endocrine and\u00a0Metabolic Diseases Shanghai Institute of Endocrine and Metabolic Diseases Department of Endocrine and Metabolic Diseases Rui\u2010Jin Hospital Shanghai Jiao\u2010Tong University School of\u00a0Medicine Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian\u2010ge","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health The National Clinical Research Center for Metabolic Diseases of Ministry of Health Rui\u2010Jin Hospital Shanghai Jiao\u2010Tong University School of Medicine E\u2010Institute of Shanghai Universities Shanghai China"},{"name":"Shanghai Clinical Center for Endocrine and\u00a0Metabolic Diseases Shanghai Institute of 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