{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T22:54:26Z","timestamp":1773269666208,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T00:00:00Z","timestamp":1578268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The number of individuals requesting medical treatment for gender dysphoria has increased significantly within the past years. Our purpose was to examine current biographic and socio\u2010demographic characteristics and aspects of legal gender reassignment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Medical files from n\u00a0=\u00a0350 individuals of a German Endocrine outpatient clinic were collected from 2009 to 2017 and analysed retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ratio of transwomen to transmen equates to 1:1.89 with a remarkable increase of transmen by the year 2013, showing a reversal of gender distribution compared with previous studies for the first time. Use of illegal substances or self\u2010initiated hormone therapy was rare (4.6 and 2.1%). Satisfaction with gender\u2010affirming hormone therapy was significantly higher in transmen than in transwomen (100% vs 96.2%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.005). Use of antidepressants declined significantly after onset of hormone treatment in transmen (13% vs 7%; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.007). The number of individuals with a graduation diploma was only about half as high as in the general population (14.3% vs 27.3%), whereas unemployment rate was more than twice as high (14% vs 6.9%). Median latency between application for legal gender reassignment and definitive court decision was 9\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our data provide possible indications for a decline of psychosocial burden in individuals diagnosed with gender dysphoria over the last years. However, affected individuals are still limited in their occupational and financial opportunities as well as by a complex and expensive procedure of legal gender reassignment in Germany.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cen.14140","type":"journal-article","created":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T14:30:55Z","timestamp":1575988255000},"page":"241-246","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Increasing normality\u2013persisting barriers: Current socio\u2010demographic characteristics of 350 individuals diagnosed with gender dysphoria"],"prefix":"10.1111","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5639-4537","authenticated-orcid":false,"given":"Gesine","family":"Meyer","sequence":"first","affiliation":[{"name":"Division of Endocrinology Department of Internal Medicine 1 Goethe\u2010University Hospital Frankfurt 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