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No previous study has investigated what proportion of men with sub\u2010fertility are exposed to adverse lifestyle factors. Furthermore, it is not known to what extent men with sub\u2010fertility are aware of lifestyle factors potentially adversely impacting their fertility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional anonymous questionnaire\u2010based study on self\u2010reported exposure and awareness of LSF was conducted in 1149 male partners of couples investigated for sub\u2010fertility in a tertiary andrology centre in London, UK.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy per cent of men investigated for sub\u2010fertility had \u22651 LSF, and twenty\u2010nine per cent had \u22652 LSF. Excessive alcohol consumption was the most common LSF (40% respondents). Seventeen per cent of respondents used recreational drugs (RD) regularly, but only 32% of RD users believed RD impair male fertility. Twenty\u2010five per cent of respondents were smokers, which is higher than the UK average (20%). Twenty\u2010seven per cent of respondents had a waist circumference (WC) &gt;36\u00a0inches (91\u00a0cm), and 4% had WC &gt;40\u00a0inches (102\u00a0cm). Seventy\u2010nine per cent of respondents wanted further lifestyle education to improve their fertility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our data suggest that men with sub\u2010fertility are as follows: (a) exposed to one or more LSF; (b) have incomplete education about how LSF may cause male sub\u2010fertility; (c) want more education about reducing LSF. Further studies are needed to investigate the potential of enhanced education of men about LSF to treat couples with sub\u2010fertility.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cen.14213","type":"journal-article","created":{"date-parts":[[2020,5,3]],"date-time":"2020-05-03T16:04:25Z","timestamp":1588521865000},"page":"312-321","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Burdens and awareness of adverse self\u2010reported lifestyle factors in men with sub\u2010fertility: A cross\u2010sectional study in 1149 men"],"prefix":"10.1111","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2578-8223","authenticated-orcid":false,"given":"Channa N.","family":"Jayasena","sequence":"first","affiliation":[{"name":"Section of Investigative Medicine Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3198-0879","authenticated-orcid":false,"given":"Aditi","family":"Sharma","sequence":"additional","affiliation":[{"name":"Section of Investigative Medicine Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Abbara","sequence":"additional","affiliation":[{"name":"Section of Investigative Medicine Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Luo","sequence":"additional","affiliation":[{"name":"Section of Investigative Medicine Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"White","sequence":"additional","affiliation":[{"name":"Section of Investigative Medicine Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie G.","family":"Hoskin","sequence":"additional","affiliation":[{"name":"Section of Investigative Medicine Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirin","family":"Khanjani","sequence":"additional","affiliation":[{"name":"Institute of Reproductive and Developmental Biology, Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike J.","family":"Crawford","sequence":"additional","affiliation":[{"name":"Department of Medicine Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan W.","family":"Ramsay","sequence":"additional","affiliation":[{"name":"Department of Urology Charing Cross Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sukhbinder","family":"Minhas","sequence":"additional","affiliation":[{"name":"Department of Urology Charing Cross Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5950-4316","authenticated-orcid":false,"given":"Waljit S.","family":"Dhillo","sequence":"additional","affiliation":[{"name":"Section of Investigative Medicine Imperial College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmx021"},{"key":"e_1_2_7_3_1","unstructured":"Human Fertilisation and Embryology Authority.Fertility Treatment in 2013: Trends and Figures. 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