{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T03:18:10Z","timestamp":1773717490549,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T00:00:00Z","timestamp":1607472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Previous quantitative studies have shown a reduced quality of life in patients treated for craniopharyngioma (CP). However, few have assessed their sexual quality of life and other issues related to patient intimacy have not yet been addressed. Standardized questionnaires limit the approach to sexuality and the exploration of patient experiences. A qualitative study, which allows in\u2010depth analysis, may represent an interesting approach to explore intimacy in women with a history of CP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the impact of a CP history on femininity and relationships in women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and patients<\/jats:title><jats:p>A qualitative study with semi\u2010structured interviews was conducted with 15 adult women treated for CP during childhood, adolescence or at childbearing age up to 40\u00a0years of age. Interviews were audio recorded, anonymized and transcribed literally. Data analysis was carried out with an inductive approach according to the grounded theory method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three main  themes were identified: (a) apparent changes leading to altered self\u2010perception that may impact on femininity and generate lower self\u2010esteem; (b) managing the hidden disabilities of the disease inducing a need for permanent control; and (c) building parenthood and couple relationships: coping with sexual dysfunction and infertility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study highlighted alterations in self\u2010perception and femininity due to body change and disability resulting from CP treatment, impacting both couple and social relationships. Interviewing women who underwent CP surgery at different ages highlighted specific needs and different expectations of medical professionals which emphasize the importance of offering both global and personalized care.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cen.14378","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T18:04:35Z","timestamp":1607623475000},"page":"880-887","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Women's perceptions of femininity after craniopharyngioma:  a qualitative study"],"prefix":"10.1111","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0716-8688","authenticated-orcid":false,"given":"Rapha\u00eblle","family":"Eydoux","sequence":"first","affiliation":[{"name":"Department of Gynecology\u2010Obstetric and Reproductive Medicine AP\u2010HM H\u00f4pital La Conception\u2010H\u00f4pital Nord  Marseille 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