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In this paper, we present three Swedish patients recently diagnosed with renin secreting tumours, two with reninomas and one with an extrarenal renin\u2010producing tumour, to illustrate diagnostic challenges. We also discuss the biochemical work\u2010up, the pros and cons of different imaging techniques (computer tomography [CT], magnetic resonance imaging and [18F]fluorodeoxyglucose\u2010positron emission tomography\u2010CT), as well as how renal vein sampling (RVC) may contribute to localisation of the tumour.<\/jats:p>","DOI":"10.1111\/cen.15069","type":"journal-article","created":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T17:44:30Z","timestamp":1714671870000},"page":"3-9","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Diagnostic challenges in patients with reninomas and extrarenal renin\u2010producing tumours"],"prefix":"10.1111","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3867-3023","authenticated-orcid":false,"given":"Botond","family":"Fabian","sequence":"first","affiliation":[{"name":"Department of Endocrinology Sk\u00e5ne University Hospital Lund 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