{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T06:17:52Z","timestamp":1771222672545,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T00:00:00Z","timestamp":1737331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T00:00:00Z","timestamp":1737331200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The relationship between iodine status and gestational diabetes mellitus (GDM) is inconclusive. This study aimed to explore the trajectories of urinary iodine concentrations (UIC) in pregnant women before GDM diagnosis and to assess the associations between maternal UIC trajectories and the risk of developing GDM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective cohort study was conducted in China. Data from 1076 pregnant women who were recruited between August 2019 and December 2021 were analyzed. GDM screening was performed at the 28th week of pregnancy. Arsenic and cerium catalysis spectrophotometry was used to measure UIC. The latent class model was used to identify distinct UIC trajectories in pregnant women, using multiple urine specimens. We evaluated the association of UIC trajectories with the risk of GDM by logistic regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Three maternal UIC trajectories were identified: (1) high\u2010stable trajectory (72.12%), (2) high\u2010decreasing trajectory (3.07%), and (3) low\u2010stable trajectory (24.81%). Compared with the pregnant women in high\u2010stable trajectory group, women in the low\u2010stable UIC trajectory group showed an increased risk of GDM before adjustment of covariates (OR: 1.58, 95% CI: 1.08\u20132.27). After adjusting for different covariates, a statistically significant association was observed only between low\u2010stable trajectory trajectories and GDM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study highlights a relationship between UIC and the risk of GDM. To better prevent iodine deficiency and GDM, persistent sufficient iodine status from pregnancy to delivery, should be emphasized.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cen.15197","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T03:08:24Z","timestamp":1737342504000},"page":"517-525","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Trajectories of Maternal Urinary Iodine Concentration Are Associated With Gestational Diabetes Mellitus"],"prefix":"10.1111","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8876-3575","authenticated-orcid":false,"given":"Yahui","family":"Li","sequence":"first","affiliation":[{"name":"School of Public Health Hangzhou Medical College Hangzhou Zhejiang China"},{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simeng","family":"Gu","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe","family":"Mo","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueqing","family":"Li","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujie","family":"Jiang","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"},{"name":"Health Science Center Ningbo University Ningbo Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenyang","family":"Liu","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"},{"name":"Anhui Provincial Center for Disease Control and Prevention Hefei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fanjia","family":"Guo","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangming","family":"Mao","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanyang","family":"Wang","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuemin","family":"Huang","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Li","sequence":"additional","affiliation":[{"name":"Zhejiang Salt Industry Group Co., Ltd Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhijian","family":"Chen","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofeng","family":"Wang","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoming","family":"Lou","sequence":"additional","affiliation":[{"name":"Zhejiang Provincial Center for Disease Control and Prevention Hangzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,20]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-019-0098-8"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.20.2516"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2021.109050"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.03.074"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.4093\/dmj.2021.0178"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-020-2759-8"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-021-04352-w"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12112705"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60731-5"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-1646"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-016-3985-5"},{"key":"e_1_2_12_13_1","unstructured":"\u201cWHO\/UNICEF\/ICCIDD \u201d Assessment of Iodine Deficiency Disorders and Monitoring Their Elimination: A Guide for Programme Managers 3rd ed accessed March 9 2024 https:\/\/www.who.int\/publications-detail-redirect\/9789241595827."},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22031228"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2024.1346452"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu8030171"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-022-02888-x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1323816"},{"issue":"1","key":"e_1_2_12_19_1","first-page":"70","article-title":"Correlation between Adipocytokines With Iodine Deficiency Criteria in Patients With Metabolic Syndrome and Type 2 Diabetes Mellitus in Carpathians Region","volume":"1","author":"Nv S.","year":"2010","journal-title":"Likars'ka Sprava"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2017.00314"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-017-1101-4"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2019.0462"},{"key":"e_1_2_12_23_1","first-page":"5","article-title":". Predictive Values of Body Mass Index and Waist Circumference to Risk Factors of Related Diseases in Chinese Adult Population","volume":"23","author":"Data collection and analysis cooperative group of china obesity working group","year":"2002","journal-title":"Chinese Journal of Epidemiology"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-S081"},{"key":"e_1_2_12_25_1","doi-asserted-by":"crossref","unstructured":"K.Wardenaar. \u201cLatent Class Growth Analysis and Growth Mixture Modeling Using R: A Tutorial for Two R\u2010Packages and a Comparison With Mplus \u201d2020 https:\/\/doi.org\/10.31234\/osf.io\/m58wx.","DOI":"10.31234\/osf.io\/m58wx"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2023.05.063"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/10705510701575396"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csda.2004.11.004"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v078.i02"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-26942-z"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2011.0197"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.12854"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2019.0516"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10030291"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1751731112001073"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13124523"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/GIM.0b013e31816b8710"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2016-1506"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgad518"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/439463"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2015.12.027"}],"container-title":["Clinical Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cen.15197","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cen.15197","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cen.15197","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T05:51:12Z","timestamp":1771221072000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cen.15197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,20]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/cen.15197"],"URL":"https:\/\/doi.org\/10.1111\/cen.15197","archive":["Portico"],"relation":{},"ISSN":["0300-0664","1365-2265"],"issn-type":[{"value":"0300-0664","type":"print"},{"value":"1365-2265","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,20]]},"assertion":[{"value":"2024-08-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}