{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:08:10Z","timestamp":1757617690765,"version":"3.44.0"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Thyroid hormonal disorders are widely discussed in the literature. These dysfunctions also influence the modulation of the cardiovascular system due to alterations in the autonomic nervous system, affecting heart rate variability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To verify the influence of thyroidian hormonal dysfunctions on the modulation of cardiac autonomic activity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic review was carried out to search for studies used in the electronic databases Virtual Health Library (VHL), Scielo, Pubmed via Medline, Cochrane, Embase, Scopus, Web of Science, Cinahl and SPORTDiscus, without restrictions how many years. For this review, we have considered experimental studies carried out with human beings that will analyse the variability of heart rate in the thyroid hormone diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten thousand two hundred ninety\u2010eight items found, 15 included, which were non\u2010randomised clinical trials that assessed heart rate variability domains. I note that patients affected by hypothyroidism or hyperthyroidism have a reduction in heart rate variability, reflecting a decrease in the adaptive capacity of the heart.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both hypothyroidism and hyperthyroidism affect cardiac autonomic modulation, resulting in a reduction in heart rate variability. However, there were differences in relation to the availability of frequency and time data.<\/jats:p><\/jats:sec>","DOI":"10.1111\/cen.15299","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T00:38:45Z","timestamp":1751589525000},"page":"407-416","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Cardiac Autonomic Function in Patients With Alteration in Thyroid Hormones: Systematic Literature Review"],"prefix":"10.1111","volume":"103","author":[{"given":"Marianne Lucena da","family":"Silva","sequence":"first","affiliation":[{"name":"Collective Health Department University of Brasilia Brasilia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00e1dia Martins de Paula","family":"Souza","sequence":"additional","affiliation":[{"name":"Physical Therapy Department University of Brasilia Brasilia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel Luciano Rodrigues da Silva","family":"J\u00fanior","sequence":"additional","affiliation":[{"name":"State University of Par\u00e1 Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda Gabriele Dantas Pinto","family":"Vieira","sequence":"additional","affiliation":[{"name":"State University of Par\u00e1 Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2574-9697","authenticated-orcid":false,"given":"Liana Barbaresco Gomide","family":"Matheus","sequence":"additional","affiliation":[{"name":"Physical Therapy Department University of Brasilia Brasilia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline Teixeira","family":"Alves","sequence":"additional","affiliation":[{"name":"Physical Therapy Department University of Brasilia Brasilia Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katiane da Costa","family":"Cunha","sequence":"additional","affiliation":[{"name":"State University of Par\u00e1 Par\u00e1 Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.18316\/sdh.v6i1.4186"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.11606\/issn.1679-9836.v98i1p82-86"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/1414-431x20187704"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0066-782x2011005000059"},{"key":"e_1_2_10_6_1","unstructured":"J.HIGGINSandS.GREEN(Ed.). 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