{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T06:13:09Z","timestamp":1788243189852,"version":"build-2803163510"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Whereas hypergonadotropic hypogonadism is incriminated for poor bone mass in adults with Turner syndrome (TS), studies are limited on bone mass acquisition in pubertal girls with this condition. In previous studies reporting low bone mass in pubertal girls with TS, the bone\u2010mineral\u2010density (BMD) was not adjusted for height, a major determinant of BMD in this group. The present study was designed to address this knowledge gap by looking at the effect of height\u2010adjustment on BMD in pre\u2010pubertal girls with TS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Eighty pre\u2010pubertal girls with TS aged 12\u201318 years who did not receive GH or pubertal induction before the study, and 85 age\u2010matched controls underwent BMD assessment by dual\u2010energy X\u2010ray absorptiometry (DXA) followed by stature corrections as per ISCD official positions. Bone turnover markers, P1NP (formation) and beta\u2010CTX (resorption) were also assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      TS patients had lower BMD both at lumbar spine (0.763\u2009\u00b1\u20090.116\u2009gm\/cm\n                      <jats:sup>2<\/jats:sup>\n                      vs. 0.938\u2009\u00b1\u20090.153\u2009gm\/cm\n                      <jats:sup>2<\/jats:sup>\n                      ,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), total\u2010body\u2010less\u2010head (0.696\u2009\u00b1\u20090.087\u2009gm\/cm2 vs. 0.761\u2009\u00b1\u20090.187\u2009gm\/cm2,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002) and non\u2010dominant distal radius (0.592\u2009\u00b1\u20090.063\u2009gm\/cm\n                      <jats:sup>2<\/jats:sup>\n                      vs. 0.690\u2009\u00b1\u20090.081\u2009gm\/cm\n                      <jats:sup>2<\/jats:sup>\n                      , =\u20090.006) compared to healthy controls. However, the differences disappeared at all sites following adjustment of the BMD values for stature using the bone mineral apparent density (BMAD) (0.275\u2009\u00b1\u20090.032\u2009gm\/cm\n                      <jats:sup>3<\/jats:sup>\n                      vs. 0.286\u2009\u00b1\u20090.047\u2009gm\/cm\n                      <jats:sup>3<\/jats:sup>\n                      ,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.357) and height adjusted Z scores (\u22120.9\u2009\u00b1\u20091.3 vs. \u22121.5\u2009\u00b1\u20093.9,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.496). The lower beta\u2010CTX values in TS indicated reduced bone resorption. (0.81\u2009\u00b1\u20090.37\u2009ng\/mL vs. 1.05\u2009\u00b1\u20090.59\u2009ng\/mL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.036).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>When adjusted for stature, bone mineral density in Turner Syndrome is not different from that of healthy girls of the same age.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/cen.70090","type":"journal-article","created":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:04:42Z","timestamp":1767168282000},"page":"463-471","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["DXA Derived Low Bone Mass in a Cohort of Prepubertal Eastern Indian Girls With Turner Syndrome Disappeared Following Adjustment for Short Stature"],"prefix":"10.1111","volume":"104","author":[{"given":"Piyas","family":"Gargari","sequence":"first","affiliation":[{"name":"Department of Endocrinology &amp; Metabolism Institute of Post Graduate Medical Education &amp; Research and SSKM Hospital Kolkata India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunetra","family":"Mondal","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Nil Ratan Sircar Medical College &amp; Hospital Kolkata"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiranjit","family":"Bose","sequence":"additional","affiliation":[{"name":"Department of Endocrinology Nil Ratan Sircar Medical College &amp; Hospital Kolkata"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5853-5249","authenticated-orcid":false,"given":"Subhankar","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Department of Endocrinology &amp; Metabolism Institute of Post Graduate Medical Education &amp; Research and SSKM Hospital Kolkata India"},{"name":"Dept. of Endocrinology Medica Superspeciality Hospital Kolkata India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8033-5748","authenticated-orcid":false,"given":"Satinath","family":"Mukhopadhyay","sequence":"additional","affiliation":[{"name":"Department of Endocrinology &amp; Metabolism Institute of Post Graduate Medical Education &amp; Research and SSKM Hospital Kolkata India"},{"name":"Indian Barcode of Life (InBOL) Kolkata India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.7.7683"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2019.09.010"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-0346"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1530\/endoabs.41.EP127"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2015.07.021"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-73-2-355"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-006-0153-y"},{"key":"e_1_2_8_9_1","unstructured":"Pediatric Positions. 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