{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T16:57:31Z","timestamp":1785776251363,"version":"3.56.0"},"reference-count":4,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Endocrinology"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This correspondence critically evaluates the diagnostic and therapeutic paradigms presented by Ekaterina Bibik et al. in their analysis of rare hereditary hypoparathyroidism involving\n                    <jats:italic>CASR<\/jats:italic>\n                    ,\n                    <jats:italic>GNA11<\/jats:italic>\n                    , and\n                    <jats:italic>GATA3<\/jats:italic>\n                    mutations. While the case series provides valuable genomic data, the reported decade\u2010long diagnostic delays\u2014particularly the misidentification of mineral disorders as primary epilepsy\u2014unmask a profound systemic failure in clinical vigilance regarding neuroimaging findings like Fahr syndrome. We emphasize that current \u201cconventional\u201d management, characterized by aggressive calcium and vitamin D supplementation, constitutes a precarious pharmacological tightrope that risks irreversible iatrogenic organ injury, as evidenced by the acute renal failure reported in Case 3. The necessity for early molecular screening is underscored not merely for academic classification but as an essential conduit to physiological homeostasis through emerging PTH analogs. Ultimately, we kindly argue for a transition from reactive symptom suppression to a precision\u2010medicine framework that mitigates the long\u2010term systemic sequelae of these rare endocrinopathies.\n                  <\/jats:p>","DOI":"10.1111\/cen.70170","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T08:41:21Z","timestamp":1781167281000},"page":"358-359","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Regarding Non\u2010Classical Presentations of Rare Hereditary Hypoparathyroidism: A Case Series of CASR, GNA11, and GATA3 Mutations in Parathyroidology"],"prefix":"10.1111","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5217-0755","authenticated-orcid":false,"given":"Ilker","family":"Sengul","sequence":"first","affiliation":[{"name":"Thyroidology Unit Giresun University Faculty of Medicine Giresun Turkey"},{"name":"Division of Endocrine Surgery Giresun University Faculty of Medicine Giresun Turkey"},{"name":"Department of General Surgery Giresun University Faculty of Medicine Giresun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0416-0621","authenticated-orcid":false,"given":"Demet","family":"Sengul","sequence":"additional","affiliation":[{"name":"Department of Pathology Giresun University Faculty of Medicine Giresun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,11]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cen.70141"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-0744"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathol.2021.02.011"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.70116"}],"container-title":["Clinical Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cen.70170","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cen.70170","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cen.70170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T16:33:13Z","timestamp":1785774793000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cen.70170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,11]]},"references-count":4,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1111\/cen.70170"],"URL":"https:\/\/doi.org\/10.1111\/cen.70170","archive":["Portico"],"relation":{},"ISSN":["0300-0664","1365-2265"],"issn-type":[{"value":"0300-0664","type":"print"},{"value":"1365-2265","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,11]]},"assertion":[{"value":"2026-04-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}