{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T14:50:12Z","timestamp":1775746212073,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical &amp; Exp Neuroim"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>As the COVID\u201019 pandemic continues to rise, the development of effective vaccines is of crucial importance to prevent further morbidity and mortality. In parallel, some rare adverse events related to COVID\u201019 vaccines, have been reported, most of them mild. Here we report the case of a previously healthy 19\u2010year\u2010old woman who developed optic neuritis 1\u00a0week after single dose of Ad26.COV2.S vaccine with marked improvement after management with steroids. Although causality cannot be confirmed due to lack of a biological marker, this case may help to guide further research for potential pathogenic mechanism.<\/jats:p>","DOI":"10.1111\/cen3.12682","type":"journal-article","created":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T16:34:10Z","timestamp":1636475650000},"page":"72-74","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Optic neuritis after COVID\u201019 vaccine application"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0668-0567","authenticated-orcid":false,"given":"Christian","family":"Garc\u00eda\u2010Estrada","sequence":"first","affiliation":[{"name":"General Hospital \u201cIgnacio Garcia Tellez\u201d Mexican Institute of Social Security  Durango Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0206-322X","authenticated-orcid":false,"given":"Enrique","family":"G\u00f3mez\u2010Figueroa","sequence":"additional","affiliation":[{"name":"National Institute of Neurology and Neurosurgery  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lennyn","family":"Alban","sequence":"additional","affiliation":[{"name":"Radiology Department Metropolitan Hospital  Quito Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8874-0964","authenticated-orcid":false,"given":"Alejandro","family":"Arias\u2010C\u00e1rdenas","sequence":"additional","affiliation":[{"name":"Neurology Department Metropolitan Hospital  Quito Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,22]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"COVID\u201019 Dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU).https:\/\/coronavirus.jhu.edu\/map.html"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2101544"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2105869"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.7517"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2021.102663"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(20)32661\u20101"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.26065"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2021.04.001"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2013.10.003"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-021-00526-x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2020.108426"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2017.151"}],"container-title":["Clinical and Experimental Neuroimmunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cen3.12682","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cen3.12682","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cen3.12682","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T16:27:05Z","timestamp":1692980825000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cen3.12682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,22]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1111\/cen3.12682"],"URL":"https:\/\/doi.org\/10.1111\/cen3.12682","archive":["Portico"],"relation":{},"ISSN":["1759-1961","1759-1961"],"issn-type":[{"value":"1759-1961","type":"print"},{"value":"1759-1961","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,22]]},"assertion":[{"value":"2021-09-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}