{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:17:28Z","timestamp":1777425448962,"version":"3.51.4"},"reference-count":9,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Tumours compressing the optic pathway may lead to irreversible loss of vision that can be detected by pattern electroretinogram owing to its relation to ganglion cell function. This study aims to assess whether pattern electroretinogram is a useful tool to predict visual outcome following decompressive surgery for sellar and parasellar tumours.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective, non\u2010randomized study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Forty eyes of 20 patients with radiologically confirmed tumours in and around the sellar region.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients were followed for 6 weeks following surgical intervention (transphenoidal or transfrontal approach).<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>Best\u2010corrected visual acuity, visual fields (<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>umphrey 30\u20102 standard automated perimetry) and pattern electroretinogram. The ratio <jats:styled-content style=\"fixed-case\">N95\/P50<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">N2\/P1<\/jats:styled-content>) was calculated for each recording.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was improvement in visual fields in 35.4% eyes with normal n2\/p1 ratio (&gt;1.1) as compared to 22.2% with abnormal ratio. Also, 9.6% eyes with normal ratio and 11.1% with an abnormal ratio deteriorated postoperatively. No association was found between pattern electroretinogram and visual fields preoperatively and postoperatively (<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.093).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pattern electroretinogram may not be a useful prognostic indicator in the preoperative assessment of tumours causing chiasmal compression. An abnormal <jats:styled-content style=\"fixed-case\">N2\/P1<\/jats:styled-content> ratio is not necessarily associated with lesser or no clinical improvement following surgery as compared to an eye with a normal pattern electroretinogram.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.12138","type":"journal-article","created":{"date-parts":[[2013,6,18]],"date-time":"2013-06-18T11:53:59Z","timestamp":1371556439000},"page":"864-869","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Evaluation of pattern <scp>ERG<\/scp> as a visual prognosticator in chiasmatic tumours"],"prefix":"10.1111","volume":"41","author":[{"given":"Jawahar L","family":"Goyal","sequence":"first","affiliation":[{"name":"Guru Nanak Eye Centre Maulana Azad Medical College  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanalyn","family":"Thangkhiew","sequence":"additional","affiliation":[{"name":"Guru Nanak Eye Centre Maulana Azad Medical College  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Usha","family":"Yadava","sequence":"additional","affiliation":[{"name":"Guru Nanak Eye Centre Maulana Azad Medical College  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ritu","family":"Arora","sequence":"additional","affiliation":[{"name":"Guru Nanak Eye Centre Maulana Azad Medical College  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parul","family":"Jain","sequence":"additional","affiliation":[{"name":"Guru Nanak Eye Centre Maulana Azad Medical College  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(55)91869-9"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.71.3.166"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1997.231"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.84.9.1024"},{"key":"e_1_2_5_6_1","first-page":"127","article-title":"Visual field defects in non\u2010functioning pituitary adenomas","volume":"50","author":"Thomas R","year":"2002","journal-title":"Indian J Ophthalmol"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2002.800510.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004170050074"},{"issue":"1","key":"e_1_2_5_9_1","first-page":"232","article-title":"An analysis of the pathophysiology and the development of treatment strategies for compressive optic nerve lesions using pattern electroretinogram and visual evoked potential","volume":"36","author":"Kaufmann D","year":"1986","journal-title":"Neurology"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(00)00539-0"}],"container-title":["Clinical &amp; Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fceo.12138","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ceo.12138","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T02:24:55Z","timestamp":1696386295000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ceo.12138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,16]]},"references-count":9,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["10.1111\/ceo.12138"],"URL":"https:\/\/doi.org\/10.1111\/ceo.12138","archive":["Portico"],"relation":{},"ISSN":["1442-6404","1442-9071"],"issn-type":[{"value":"1442-6404","type":"print"},{"value":"1442-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,16]]},"assertion":[{"value":"2012-10-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-04-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-07-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}