{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:46:46Z","timestamp":1787014006005,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,9,9]],"date-time":"2014-09-09T00:00:00Z","timestamp":1410220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2015,3]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n To assess the choroidal thickness (\n CT<\/jats:styled-content>\n ) in patients with obstructive sleep apnoea syndrome (\n OSAS<\/jats:styled-content>\n ) and healthy controls.\n <\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Prospective, cross\u2010sectional study<\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n \n Ninety\u2010two eyes of 92 patients with\n OSAS<\/jats:styled-content>\n and 32 eyes of 32 aged and body mass index\u2010matched healthy subjects were enrolled.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n OSAS<\/jats:styled-content>\n patients were further divided into mild, moderate and severe\n OSAS<\/jats:styled-content>\n groups according to their apnoea hypopnea index (\n AHI<\/jats:styled-content>\n ) values. The macular\n CT<\/jats:styled-content>\n and peripapillary retinal nerve fibre layer (\n RNFL<\/jats:styled-content>\n ) thickness measurements of the subjects were obtained using spectral domain optical coherence tomography (\n RTV<\/jats:styled-content>\n ue\u2010100,\n O<\/jats:styled-content>\n ptovue). The\n CT<\/jats:styled-content>\n and\n RNFL<\/jats:styled-content>\n thickness measurements of the groups were compared, and correlations among the\n AHI<\/jats:styled-content>\n values and these measurements were calculated.\n <\/jats:p>\n <\/jats:sec>\n \n Main Outcome Measures<\/jats:title>\n Choroidal thickness.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n There were no significant differences in subfoveal and temporal\n CT<\/jats:styled-content>\n measurements of the groups. A pairwise comparison between the groups revealed that severe\n OSAS<\/jats:styled-content>\n group has significantly thinner\n CT<\/jats:styled-content>\n than mild\n OSAS<\/jats:styled-content>\n group at 3.0\u2009mm nasal to the fovea. Also, compared with severe\n OSAS<\/jats:styled-content>\n group, the\n CT<\/jats:styled-content>\n measurements at 1.5\u2009mm and 3.0\u2009mm nasal to the fovea were significantly thicker in control eyes (both,\n P<\/jats:italic>\n \u2009<\u20090.05). There were weak negative correlations between the nasal\n CT<\/jats:styled-content>\n measurements and\n AHI<\/jats:styled-content>\n in the\n OSAS<\/jats:styled-content>\n group (nasal 1.5\u2009mm,\n P<\/jats:italic>\n \u2009=\u20090.002,\n r<\/jats:italic>\n \u2009=\u2009\u22120.358; nasal 3.0\u2009mm,\n P<\/jats:italic>\n \u2009=\u20090.004,\n r<\/jats:italic>\n \u2009=\u2009\u22120.336). Compared with controls, severe\n OSAS<\/jats:styled-content>\n group had significantly thinner nasal and superior\n RNFL<\/jats:styled-content>\n thickness measurement.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Sleep apnoea patients had choroidal structural alterations that may have significance on the pathophysiology of the ophthalmic disorders associated with\n OSAS<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ceo.12384","type":"journal-article","created":{"date-parts":[[2014,7,4]],"date-time":"2014-07-04T00:12:14Z","timestamp":1404432734000},"page":"139-144","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Evaluation of the macular choroidal thickness using spectral optical coherence tomography in patients with obstructive sleep apnoea syndrome"],"prefix":"10.1111","volume":"43","author":[{"given":"Hasan A","family":"Bayhan","sequence":"first","affiliation":[{"name":"Ophthalmology Department Bozok University Faculty of Medicine Yozgat Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seray","family":"Aslan Bayhan","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Bozok University Faculty of Medicine Yozgat Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yavuz S","family":"\u0130ntepe","sequence":"additional","affiliation":[{"name":"Clinic of Chest Diseases Bozok University Faculty of Medicine Yozgat Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ersin","family":"Muhafiz","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Bozok University Faculty of Medicine Yozgat Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Canan","family":"G\u00fcrdal","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Bozok University Faculty of Medicine Yozgat Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,9,9]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"667","volume-title":"Principles and Practice of Sleep Medicine","author":"Guilleminault C","year":"1994"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.12.017"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61622-0"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2005.08.010"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/02713683.2013.824986"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e32833f00dc"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.3129\/can j ophthalmol.i07-029"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.1.188"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/rr79"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(98)95030-8"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-0372"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2009.12.002"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1081\/CEH-48874"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2012.12.001"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.07.002"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27497"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.2766"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2012.02768.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.116.5.589"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3181be0a83"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e32835d9245"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.3341\/kjo.1999.13.2.100"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00063198-200011000-00003"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2000.278.6.R1667"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1385\/JMN:21:1:57"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1159\/000055622"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2013.307"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.3928\/15428877-20110627-07"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/33.6.811"},{"key":"e_1_2_5_31_1","first-page":"385","article-title":"Foveolar choroidal blood flow in age\u2010related macular degeneration","volume":"39","author":"Grunwald JE","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004424-196701000-00016"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(98)00437-1"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-013-2268-9"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2014.01.028"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(99)00026-0"}],"container-title":["Clinical & Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fceo.12384","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ceo.12384","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T20:52:46Z","timestamp":1696279966000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ceo.12384"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,9]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1111\/ceo.12384"],"URL":"https:\/\/doi.org\/10.1111\/ceo.12384","archive":["Portico"],"relation":{},"ISSN":["1442-6404","1442-9071"],"issn-type":[{"value":"1442-6404","type":"print"},{"value":"1442-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,9]]},"assertion":[{"value":"2014-04-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-06-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-09-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}