{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T02:05:31Z","timestamp":1774317931966,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,10,9]],"date-time":"2014-10-09T00:00:00Z","timestamp":1412812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To evaluate the reproducibility of intraocular pressure peaks and fluctuation elicited during the water drinking test in treated glaucomatous patients with a long follow\u2010up interval.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective cohort study in a tertiary care practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Thirty\u2010four treated primary open\u2010angle glaucoma patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients underwent the water drinking test performed in two consecutive visits without any change in the therapeutic regimen. The mean interval between tests was 4.85 (range: 3\u20136) months. Reproducibility of peak and fluctuation during the water drinking test was assessed using intraclass correlation coefficients. Bland\u2013Altman analysis was used to assess the agreement of intraocular pressure peaks and fluctuation measured between two consecutive tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>Intraclass correlation and agreement of intraocular pressure peaks and fluctuation between visits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no significant differences in baseline intraocular pressure values (mean\u2009\u00b1\u2009standard deviation, 11.73\u2009\u00b1\u20092.36 and 11.61\u2009\u00b1\u20092.71\u2009mmHg; <jats:italic>P<\/jats:italic>\u2009=\u20090.72) and peaks (14.55\u2009\u00b1\u20093.41 and 15.02\u2009\u00b1\u20093.66\u2009mmHg, respectively; <jats:italic>P<\/jats:italic>\u2009=\u20090.163) detected during the water drinking test between the first and second visits. There was also no significant difference between the average intraocular pressure fluctuation values (2.82\u2009\u00b1\u20091.99 and 3.41\u2009\u00b1\u20092.54\u2009mmHg, respectively; <jats:italic>P<\/jats:italic>\u2009=\u20090.135). Intraocular pressure peaks and fluctuation presented intraclass correlation coefficients of 0.85 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and 0.50 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results demonstrate excellent reproducibility of intraocular pressure peaks during the water drinking test. Intraocular pressure fluctuation did not reveal good reproducibility, though. These results emphasize the applicability of this test to assess treatment efficacy in daily practice and interventional studies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.12434","type":"journal-article","created":{"date-parts":[[2014,9,11]],"date-time":"2014-09-11T16:25:45Z","timestamp":1410452745000},"page":"228-233","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Reproducibility of the water drinking test in treated glaucomatous patients"],"prefix":"10.1111","volume":"43","author":[{"given":"Mirko","family":"Babic","sequence":"first","affiliation":[{"name":"Ophthalmology Clinic University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C Gustavo","family":"De Moraes","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Columbia University Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo","family":"Hatanaka","sequence":"additional","affiliation":[{"name":"Ophthalmology Clinic University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guilherme","family":"Ju","sequence":"additional","affiliation":[{"name":"Ophthalmology Clinic University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Remo","family":"Susanna","sequence":"additional","affiliation":[{"name":"Ophthalmology Clinic University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,9]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"569","article-title":"Untersuchungen \u00fcber Kapillarendothelst\u00f6rungen bei Glaukoma simplex","volume":"98","author":"Schmidt K","year":"1928","journal-title":"Arch Augenheilkd"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.58.1.55"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1976.tb00427.x"},{"key":"e_1_2_5_5_1","first-page":"1","article-title":"Importance of outflow facility","volume":"3","author":"Brubaker RF","year":"2001","journal-title":"IGR"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/108076802321021036"},{"key":"e_1_2_5_7_1","first-page":"1076","article-title":"[Use of water drinking test after non\u2010penetrating deep sclerectomy.]","volume":"28","author":"Guedes RA","year":"2005","journal-title":"J Fr Ophtalmol"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-2918(04)90075-6"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2009.02183.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2005.21.250"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e318168f008"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-0268"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.070649"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1807-59322008000400004"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2009.02003.x"},{"key":"e_1_2_5_16_1","volume-title":"Evaluation of Precision Performance of Quantitative Measurement Methods","author":"Clinical and Laboratory Standards Institute","year":"2004"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2012.02882.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.86.2.420"},{"key":"e_1_2_5_19_1","first-page":"569","volume-title":"Fundamentals of Biostatistics","author":"Rosner B","year":"2011"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2008.01765.x"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2004.058230"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-27492009000300002"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2012.07.012"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2011.72"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2011.0081"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.117.5.573"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01167-3"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(03)00478-1"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(00)00538-9"}],"container-title":["Clinical &amp; 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