{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T18:08:08Z","timestamp":1793210888276,"version":"4.5.0"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,10,30]],"date-time":"2014-10-30T00:00:00Z","timestamp":1414627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To assess the impact of cataract on quality of life (<jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content>) for patients with glaucoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Cross\u2010sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Two hundred forty\u2010two patients with mild (<jats:italic>n<\/jats:italic>\u2009=\u200967), moderate (<jats:italic>n<\/jats:italic>\u2009=\u200980) or severe (<jats:italic>n<\/jats:italic>\u2009=\u200945) glaucoma and 50 controls (glaucoma suspects). Patients with cataract of any severity were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The following data were collected: sociodemographic information, phakic\/pseudophakic status, cataract grade according to the <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>ens <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>pacities <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>lassification <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ystem (<jats:styled-content style=\"fixed-case\">LOCS<\/jats:styled-content>) <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>, visual acuity and visual field test parameters. Glaucoma severity was stratified according to binocular visual field loss. Visually significant cataract was defined as: <jats:styled-content style=\"fixed-case\">LOCS III<\/jats:styled-content> criteria nuclear cataract \u22653\/6.9, cortical cataract \u22653\/5.9 or posterior subcapsular cataract \u22652\/5.9.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>Patients\u2019 <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> was measured using <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>asch\u2010transformed scores from the <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>laucoma <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ctivity <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>imitation\u20109 (<jats:styled-content style=\"fixed-case\">GAL<\/jats:styled-content>\u20109) questionnaire. Multiple linear regression models were used to determine the association between cataract and <jats:styled-content style=\"fixed-case\">GAL<\/jats:styled-content>\u20109 (logit) score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010six (23.1%) patients had at least one visually significant cataract. At least one visually significant cataract (standardized coefficient [\u03b2] 1.19, 95% confidence interval 1.04\u20131.34, <jats:italic>P<\/jats:italic>\u2009=\u20090.011) and poor visual field index (better eye) (\u03b2 1.47, 95% confidence interval 1.36\u20131.88, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) were independently associated with worse <jats:styled-content style=\"fixed-case\">GAL<\/jats:styled-content>\u20109 score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cataract influences glaucoma\u2010related <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> among glaucoma patients of all severity levels and is an important cause of potentially reversible visual impairment among glaucoma patients. The <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>asch\u2010analysed <jats:styled-content style=\"fixed-case\">GAL<\/jats:styled-content>\u20109 questionnaire is a useful metric to quantify visual disability related to cataract in glaucoma patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.12454","type":"journal-article","created":{"date-parts":[[2014,10,8]],"date-time":"2014-10-08T11:54:06Z","timestamp":1412769246000},"page":"335-341","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Cataract and quality of life in patients with glaucoma"],"prefix":"10.1111","volume":"43","author":[{"given":"Simon E","family":"Skalicky","sequence":"first","affiliation":[{"name":"Discipline of Ophthalmology University of Sydney  Sydney New South Wales Australia"},{"name":"Centre for Eye Research Australia University of Melbourne  Melbourne Victoria Australia"},{"name":"Department of Ophthalmology Addenbrooke's 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