{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T06:50:41Z","timestamp":1791960641305,"version":"4.3.4"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,1,15]],"date-time":"2015-01-15T00:00:00Z","timestamp":1421280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2015,7]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>In this study, a conjunctival\u2010sparing ab interno approach for circumferential trabeculotomy, termed micro\u2010invasive suture trabeculotomy (MIST<\/jats:styled-content>) and its preliminary results are presented.<\/jats:p><\/jats:sec>Design<\/jats:title>Retrospective case\u2010series in a university setting.<\/jats:p><\/jats:sec>Participants<\/jats:title>A total of 31 patients with open\u2010angle glaucoma with history of canaloplasty.<\/jats:p><\/jats:sec>Methods<\/jats:title>A conjunctival\u2010sparing ab interno approach for circumferential trabeculotomy, termed MIST<\/jats:styled-content>.<\/jats:p><\/jats:sec>Main Outcome Measures<\/jats:title>Mean decrease of intraocular pressure (IOP<\/jats:styled-content>) and number of pressure\u2010lowering medications.<\/jats:p><\/jats:sec>Results<\/jats:title>Mean decrease of IOP<\/jats:styled-content> was 11.1\u2009mmHg (standard deviation [SD<\/jats:styled-content>], 9.9\u2009mmHg) at 6 months, 12.1\u2009mmHg (SD<\/jats:styled-content>, 10.5\u2009mmHg) at 12 months and 13.5\u2009mmHg (SD<\/jats:styled-content>, 11.4\u2009mmHg) at 24 months. The average percent lowering of IOP<\/jats:styled-content> was 36.7% (SD<\/jats:styled-content>, 32.8%) at 6 months, 41.4% (SD<\/jats:styled-content>, 35.9%) at 12 months and 44.6% (SD<\/jats:styled-content>, 37.7%) at 24 months. The number of pressure\u2010lowering medications decreased by 1.1 (SD<\/jats:styled-content>, 1.3) at month 6, by 1.2 (SD<\/jats:styled-content>, 1.5) at month 12, and by 1.3 (SD<\/jats:styled-content>, 1.6) at month 24.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>MIST<\/jats:styled-content> is a promising approach for the treatment of open\u2010angle glaucoma, which is insufficiently controlled with canaloplasty. The procedure achieved significant and sustained lowering of the intraocular pressure and demonstrated an excellent safety profile. The main advantages of the procedure are: easy to learn, fast to perform, and sparing of the conjunctiva for further filtration surgery, if necessary.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.12482","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T02:59:12Z","timestamp":1418698752000},"page":"409-414","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Micro\u2010invasive suture trabeculotomy after canaloplasty: preliminary results"],"prefix":"10.1111","volume":"43","author":[{"given":"Bogomil","family":"Voykov","sequence":"first","affiliation":[{"name":"Centre for Ophthalmology University Hospital T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Szurman","sequence":"additional","affiliation":[{"name":"Centre for Ophthalmology University Hospital T\u00fcbingen T\u00fcbingen Germany"},{"name":"Department of Ophthalmology, Vitreoretinal Diseases Knappschaft Eye Hospital Sulzbach Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Spyridon","family":"Dimopoulos","sequence":"additional","affiliation":[{"name":"Centre for Ophthalmology University Hospital T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Focke","family":"Ziemssen","sequence":"additional","affiliation":[{"name":"Centre for Ophthalmology University Hospital T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Alnahrawy","sequence":"additional","affiliation":[{"name":"Centre for Ophthalmology University Hospital T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,1,15]]},"reference":[{"key":"e_1_2_5_2_1","article-title":"Circumferential viscodilation of Schlemm's canal with a flexible microcannula during non\u2010penetrating glaucoma surgery","volume":"12","author":"Cameron B","year":"2006","journal-title":"Digit J Ophthalmol"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.03.051"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.163170"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.10.055"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-011-1728-3"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/469609"},{"key":"e_1_2_5_8_1","unstructured":"BrusiniP TosoniC.Trabeculectomy outcomes after a failed canaloplasty. 11th EGS Congress; 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