{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:38Z","timestamp":1783555238089,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T00:00:00Z","timestamp":1435104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To evaluate the long\u2010term effects of combined endoscopic cyclophotocoagulation and phacoemulsification (phaco) <jats:italic>versus<\/jats:italic> phacoemulsification alone on intraocular pressure control and medication reliance in the treatment of mild to moderate glaucoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective chart review in private practice setting by glaucoma fellowship trained surgeons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>A total of 261 eyes in the combined phaco\u2010endoscopic cyclophotocoagulation group with 52 eyes in the phaco\u2010alone group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Comparison of phaco\u2010endoscopic cyclophotocoagulation with phaco alone over 36 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>Full and qualified success cumulative survival, intraocular pressure and medication reliance 6\u201336 months compared with baseline. Full success was defined as minimum 20% intraocular pressure reduction with a decrease of at least one ocular hypertensive medication. Qualified success was defined as intraocular pressure no higher than baseline with a decrease of at least one ocular hypertensive medication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 36 months, mean intraocular pressure in the combined phaco\u2010endoscopic cyclophotocoagulation group was 14.6\u2009mmHg, whereas the phaco\u2010alone group was 15.5\u2009mmHg (<jats:italic>P<\/jats:italic>\u2009=\u20090.34). Mean medication reliance in the combined phaco\u2010endoscopic cyclophotocoagulation group was 0.2 medications, whereas the phaco\u2010alone group was 1.2 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Full success in the phaco\u2010endoscopic cyclophotocoagulation group was 61.4%; the phaco\u2010alone group was 23.3% (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Qualified success survival was 72.6% in the phaco\u2010endoscopic cyclophotocoagulation group and 23.3% in the phaco\u2010alone group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Combined phaco\u2010endoscopic cyclophotocoagulation effectively lowers or maintains intraocular pressure and results in ocular hypertensive medication reduction up to 36 months when compared with phaco alone. Therefore, phaco\u2010endoscopic cyclophotocoagulation may help to increase medication compliance and reduce glaucoma progression in mild to moderate glaucoma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.12510","type":"journal-article","created":{"date-parts":[[2015,2,13]],"date-time":"2015-02-13T12:21:09Z","timestamp":1423830069000},"page":"531-539","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":71,"title":["Combined endoscopic cyclophotocoagulation and phacoemulsification <i>versus<\/i> phacoemulsification alone in the treatment of mild to moderate glaucoma"],"prefix":"10.1111","volume":"43","author":[{"given":"Michael J","family":"Siegel","sequence":"first","affiliation":[{"name":"Glaucoma Center of Michigan  Southfield Michigan USA"},{"name":"Kresge Eye Institute Wayne State University  Detroit Michigan USA"},{"name":"Department of Ophtalmology William Beaumont Hospital  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Whitney S","family":"Boling","sequence":"additional","affiliation":[{"name":"Glick Eye Institute Indiana University  Indianapolis Indiana USA"},{"name":"Boling Vision Center  Elkhart Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar S","family":"Faridi","sequence":"additional","affiliation":[{"name":"Connecticut Eye Physicians and Surgeons, PC.  Milford Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chirag K","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Ophtalmology William Beaumont Hospital  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaesik","family":"Kim","sequence":"additional","affiliation":[{"name":"Kresge Eye Institute Wayne State University  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard C","family":"Boling","sequence":"additional","affiliation":[{"name":"Boling Vision Center  Elkhart Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew E","family":"Citron","sequence":"additional","affiliation":[{"name":"Glaucoma Center of Michigan  Southfield Michigan USA"},{"name":"Department of Ophtalmology William Beaumont Hospital  Royal Oak Michigan USA"},{"name":"Department of Ophthalmology St. John Providence Hospital\u2010Michigan State University  Madison Heights Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc J","family":"Siegel","sequence":"additional","affiliation":[{"name":"Glaucoma Center of Michigan  Southfield Michigan USA"},{"name":"Department of Ophtalmology William Beaumont Hospital  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Les I","family":"Siegel","sequence":"additional","affiliation":[{"name":"Glaucoma Center of Michigan  Southfield Michigan USA"},{"name":"Department of Ophtalmology William Beaumont Hospital  Royal Oak Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1950.02910300027006"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-09408-3_13"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-199504000-00005"},{"key":"e_1_2_5_5_1","first-page":"61","article-title":"Combined phacoemulsification and ECP","author":"Berke SJ","year":"2008","journal-title":"Cataract Refract Surg Today"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102011\u2010000578"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.12051"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.12.045"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.02.050"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ijg.0000212294.31411.92"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2004.047662"},{"key":"e_1_2_5_12_1","first-page":"347","article-title":"Effect of phacoemulsification on intraocular pressure","volume":"21","author":"Jamil AZ","year":"2011","journal-title":"J Coll Physicians Surg Pak"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e3283360ac3"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2011.02617.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.06.021"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)71696-4"},{"key":"e_1_2_5_17_1","unstructured":"BerkeSJ SturmRT CaroniaRM.Phacoemulsification combined with endoscopic cyclophotocoagulation (ECP) in the management of cataract and medically controlled glaucoma: a large long\u2010term study.AGS Annual Meeting; March 6 2006; Charleston SC and at the AAO Annual Meeting; November 14 2006; Las Vegas NV."},{"key":"e_1_2_5_18_1","unstructured":"The ECP Study Group.Comparison of phaco\u2010ECP to phaco alone in 1000 glaucoma patients; a randomized prospective study including fluorescein angiography in all patients in both groups. 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