{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T08:13:16Z","timestamp":1696407196337},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,10,12]],"date-time":"2015-10-12T00:00:00Z","timestamp":1444608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this study is to report the 6\u2010year incidence of age\u2010related cataract in a population\u2010based study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>The design used is a population\u2010based cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>A cohort of 2484 phakic subjects, aged 40\u2009years and above at baseline, from a south Indian population was included in the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Bilateral phakics with visual acuity of 6\/12 or better and cataract less than N2, C2 and P2 on the Lens Opacities Classification System II at baseline were included. Subjects with glaucoma and corneal or retinal diseases were excluded. Incident visually significant cataract was defined as visual acuity of less than 6\/18 with a corresponding one grade or greater change in Lens Opacities Classification System II or history of having undergone cataract surgery with evidence of pseudophakia or aphakia at the 6\u2010year follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>Six\u2010year incidence of visually significant cataract and associated risk factors data were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Incident visually significant cataract at 6\u2009years was seen in 158 subjects (6.36%, 95% CI: 5.40\u20137.32, phakics:pseudophakics\/aphakics 70:88). Incidence was higher in the rural cohort as compared with the urban cohort (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Incidence increased with age and was highest in the \u226570\u2009years age group (odds ratio (OR):31.23, 95% CI: 15.20\u201364.16, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Other associated risk factors included illiteracy (OR 1.75, 95% CI: 1.17\u20132.61, <jats:italic>P<\/jats:italic>\u2009=\u20090.007) and smoking (OR 1.77, 95% CI: 1.08\u20132.88, <jats:italic>P<\/jats:italic>\u2009=\u20090.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A significant proportion of the population developed visually significant age\u2010related cataract at 6\u2009years. Incident visually significant cataract was significantly greater for the rural cohort between 50 and 69\u2009years\u2009old.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.12636","type":"journal-article","created":{"date-parts":[[2015,8,20]],"date-time":"2015-08-20T06:44:52Z","timestamp":1440053092000},"page":"114-120","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Six\u2010year incidence of visually significant age\u2010related cataract: the Chennai eye disease incidence study"],"prefix":"10.1111","volume":"44","author":[{"given":"Manish","family":"Panday","sequence":"first","affiliation":[{"name":"Glaucoma Project Medical and Vision Research Foundation, Sankara Nethralaya  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronnie","family":"George","sequence":"additional","affiliation":[{"name":"Glaucoma Project Medical and Vision Research Foundation, Sankara Nethralaya  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rashima","family":"Asokan","sequence":"additional","affiliation":[{"name":"Glaucoma Project Medical and Vision Research Foundation, Sankara Nethralaya  Chennai India"},{"name":"Elite School of Optometry  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satyamangalam","family":"Ve Ramesh","sequence":"additional","affiliation":[{"name":"Glaucoma Project Medical and Vision Research Foundation, Sankara Nethralaya  Chennai India"},{"name":"Elite School of Optometry  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lokapavani","family":"Velumuri","sequence":"additional","affiliation":[{"name":"Glaucoma Project Medical and Vision Research Foundation, Sankara Nethralaya  Chennai India"},{"name":"Elite School of Optometry  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil S","family":"Choudhari","sequence":"additional","affiliation":[{"name":"Glaucoma Project Medical and Vision Research Foundation, Sankara Nethralaya  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachi Devi","family":"Boddupalli","sequence":"additional","affiliation":[{"name":"Glaucoma Project Medical and Vision Research Foundation, Sankara Nethralaya  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Govindan T","family":"Sunil","sequence":"additional","affiliation":[{"name":"Glaucoma Project Medical and Vision Research Foundation, Sankara Nethralaya  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingam","family":"Vijaya","sequence":"additional","affiliation":[{"name":"Glaucoma Project Medical and Vision Research Foundation, Sankara Nethralaya  Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,10,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2011-300539"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1997.01100150107018"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(92)31934-7"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(97)30266-8"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1990.01070040138048"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)70128-X"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.116.5.653"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.01.026"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.05.020"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.85.6.635"},{"key":"e_1_2_5_12_1","unstructured":"Eleventh revision of the International Statistical Classification of Diseases and Related Health Problems.World Health Organization. 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