{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T15:38:30Z","timestamp":1766504310316},"reference-count":10,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2016,6,7]],"date-time":"2016-06-07T00:00:00Z","timestamp":1465257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The background of this study is to introduce the surgical technique and outcomes of a novel membrane\u2010tube (MT) type glaucoma shunt device (MicroMT), which was developed to achieve safer and more predictable intraocular pressure (IOP) control compared with conventional trabeculectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>This is a retrospective, non\u2010comparative, interventional case series study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>The MicroMT was implanted in 43 glaucomatous eyes with insufficient IOP control despite medical treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The MicroMT consists of an expanded polytetrafluoroethylene membrane and a silicone tube with an intraluminal stent, which allows aqueous drainage from the anterior chamber to the lamellar scleral flap. The intraluminal stent prevents excessive aqueous drainage and allows additional IOP reduction through retraction or removal of the stent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>The main outcome measures of this study are IOP changes and complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean (SD) IOP decreased from a preoperative value of 22.5 (6.9) mmHg to 11.1 (3.6) mmHg 3\u2009years after the operation (50.7% reduction from baseline; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). Intraluminal stent removal 4\u2009weeks after the operation induced an additional 40.2% IOP reduction (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). When success was defined as an IOP between 6 and 21\u2009mmHg, and an IOP reduction of \u226520% from baseline, the success rate was 89.5% at 3\u2009years after the operation. No postoperative ocular hypotony (IOP &lt;6\u2009mmHg) or tube\u2010related complications occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>MicroMT implantation is a novel therapy that may reduce IOP safely and effectively, with no apparent risk of postoperative ocular hypotony. Glaucoma surgery using this device may be a good alternative to conventional glaucoma surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.12772","type":"journal-article","created":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T16:08:25Z","timestamp":1462378105000},"page":"776-782","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Novel membrane\u2010tube type glaucoma shunt device for glaucoma surgery"],"prefix":"10.1111","volume":"44","author":[{"given":"Byung Heon","family":"Ahn","sequence":"first","affiliation":[{"name":"Kim's Eye Hospital, Myung\u2010Gok Eye Research Institute, Department of Ophthalmology Konyang University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Hoon","family":"Hwang","sequence":"additional","affiliation":[{"name":"Kim's Eye Hospital, Myung\u2010Gok Eye Research Institute, Department of Ophthalmology Konyang University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Chul","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Samsung Medical Center, School of Medicine Sungkyunkwan University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.10.024"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-199504000-00002"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01069-2"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.87.1.63"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3341\/kjo.2003.17.2.106"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.09.014"},{"key":"e_1_2_5_8_1","article-title":"Ex\u2010PRESS implantation versus trabeculectomy in uncontrolled glaucoma: a meta\u2010analysis","volume":"8","author":"Wang W","year":"2013","journal-title":"PLoS One"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-16625"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-200104000-00011"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2012.01.008"}],"container-title":["Clinical &amp; Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fceo.12772","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fceo.12772","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ceo.12772","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T19:18:34Z","timestamp":1696360714000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ceo.12772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,7]]},"references-count":10,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1111\/ceo.12772"],"URL":"https:\/\/doi.org\/10.1111\/ceo.12772","archive":["Portico"],"relation":{},"ISSN":["1442-6404","1442-9071"],"issn-type":[{"value":"1442-6404","type":"print"},{"value":"1442-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,7]]},"assertion":[{"value":"2016-03-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-04-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-06-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}