{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T06:04:08Z","timestamp":1774073048981,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,2,8]],"date-time":"2017-02-08T00:00:00Z","timestamp":1486512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>A<jats:sc>bstract<\/jats:sc><\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To describe the clinical spectrum of presumed tuberculous (TB) uveitis in a developed, non\u2010endemic country of high immigrant population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective review of a consecutive case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>All 39 patients diagnosed with presumed TB uveitis at the tertiary uveitis service in Auckland from 2007 to 2014.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Clinical chart review.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>Patient demographics, risk factors, ophthalmic manifestations, management and outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age was 37\u00a0years (interquartile range [IQR] 31\u201352) and 56% were female. The majority (97%) were born outside of New Zealand, and 77% had no TB\u2010related history. Radiological abnormalities consistent with TB were evident in seven patients, including three who had culture positive pulmonary disease. Anterior uveitis was diagnosed in ten patients (26%), anterior and intermediate uveitis in eight (21%), posterior uveitis in 13 (33%) and panuveitis in eight (21%). Sixteen (41%) had retinal vasculitis, and five (13%) had multifocal serpiginoid choroiditis. Common complications included cataract (51%), ocular hypertension (36%), broad posterior synechiae (33%) and cystoid macular oedema (28%). Anti\u2010TB treatment was initiated in 30 patients (76%). All but three patients completed the intended course of six to 12\u00a0months. Following anti\u2010TB treatment, 67% remained in remission for at least 12\u00a0months, and all but two patients successfully stopped systemic steroids. The median initial and final visual acuity was 6\/9 (IQR 6\/6\u20136\/18) and 6\/6 (IQR 6\/6\u20136\/9), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Despite a wide range of ocular presentations and complications, our cohort demonstrated good remission rate and visual prognosis following anti\u2010TB treatment in carefully selected patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.12881","type":"journal-article","created":{"date-parts":[[2016,11,29]],"date-time":"2016-11-29T03:52:45Z","timestamp":1480391565000},"page":"357-365","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Presumed tuberculous uveitis in non\u2010endemic country for tuberculosis: case series from a New Zealand tertiary uveitis clinic"],"prefix":"10.1111","volume":"45","author":[{"given":"Ken K","family":"Ng","sequence":"first","affiliation":[{"name":"Ophthalmology Department Greenlane Clinical Centre Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitzi","family":"Nisbet","sequence":"additional","affiliation":[{"name":"Infectious Disease Department Auckland City Hospital Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika M","family":"Damato","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Greenlane Clinical Centre Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne L","family":"Sims","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Greenlane Clinical Centre Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,2,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.7.677"},{"key":"e_1_2_6_3_1","volume-title":"Global Tuberculosis Report 2014","author":"World Health Organisation","year":"2014"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(03)00741-2"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7395.909"},{"key":"e_1_2_6_6_1","unstructured":"World Health Organisation.Global tuberculosis report 2015 [Internet].2015[cited 2016 Aug 19]. 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