{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T20:45:09Z","timestamp":1778359509247,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T00:00:00Z","timestamp":1531180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Importance<\/jats:title><jats:p>Using an ophthalmic viscoelastic device to manage early postoperative hypotony after Baerveldt glaucoma implant (BGI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>To determine the outcome of intracameral sodium hyaluronate injection for early postoperative hypotony treatment after BGI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A retrospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>One\u2010hundred\u2010and\u2010thirty\u2010eight patients (176 eyes) had BGI from January 2012 to November 2015. Those who had hypotony within 3 months postoperatively were studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Hypotonous eyes were injected with 0.1 mL sodium hyaluronate 1.4% intracameral on the slit\u2010lamp. The patients were followed up weekly and the injection repeated up to 3 times if hypotony persisted. The tube was tied surgically as a last resort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>The intraocular pressure and best\u2010corrected visual acuity at week 1, 2, 3, 4, 6 and month 4 were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty (17.0%) out of 176 eyes developed early postoperative hypotony. The median intraocular pressure and median best\u2010corrected visual acuity when hypotony first presented were 3 mmHg and 0.8 logMAR. Two eyes were excluded as they had more than 0.1 mL injection. Eight (29%) of the 28 hypotonous eyes resolved after one injection, seven (25%) required two and 10 (36%) needed three injections. Three (11%) eyes had surgical tube tie. The median intraocular pressures were 5, 7, 8, 10, 11 and 13 mmHg at week 1, 2, 3, 4, 6 and month 4 post\u2010injection. The median best\u2010corrected visual acuity were 0.60, 0.50, 0.50, 0.45, 0.40 and 0.40 logMAR for the same period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Relevance<\/jats:title><jats:p>Standardised intracameral 0.1 mL sodium hyaluronate 1.4% is an effective and safe way to manage early postoperative hypotony after BGI.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.13347","type":"journal-article","created":{"date-parts":[[2018,6,23]],"date-time":"2018-06-23T06:23:47Z","timestamp":1529735027000},"page":"1035-1040","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Outcome of fixed volume intracameral sodium hyaluronate 1.4% injection for early postoperative hypotony after Baerveldt glaucoma implant"],"prefix":"10.1111","volume":"46","author":[{"given":"Patrick J","family":"Chiam","sequence":"first","affiliation":[{"name":"Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust  Birmingham UK"},{"name":"Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust  Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2377-9056","authenticated-orcid":false,"given":"Xiaoli","family":"Chen","sequence":"additional","affiliation":[{"name":"Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust  Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M Sayeed","family":"Haque","sequence":"additional","affiliation":[{"name":"Institute of Applied Health Research, University of Birmingham  Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5708-2540","authenticated-orcid":false,"given":"Velota CT","family":"Sung","sequence":"additional","affiliation":[{"name":"Birmingham and Midland Eye Centre, Sandwell and West Birmingham Hospitals NHS Trust  Birmingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,7,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.08.043"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.116.5.571"},{"key":"e_1_2_5_4_1","first-page":"343","volume-title":"Contemporary Ophthalmology, Honouring Sir Steward Duke\u2010Elder","author":"Gass JDM","year":"1972"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(02)01640-1"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-199447030-00009"},{"key":"e_1_2_5_7_1","unstructured":"ShaarwayTM SherwoodMB GrehnF. 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