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They may present as the following: Firstly, granulomatous cluster of small and medium\u2010sized keratic precipitates in Arlt's triangle, with or without corneal scars, suggestive of herpes simplex or varicella\u2010zoster virus infection. Secondly, Posner\u2010Schlossman syndrome with few medium\u2010sized keratic precipitates, minimal anterior chamber cells and extremely high intraocular pressure; this is mainly associated with cytomegalovirus. Thirdly, Fuchs uveitis syndrome, with fine stellate keratic precipitates diffusely distributed over the corneal endothelium, with diffuse iris stromal atrophy but without posterior synechiae, is associated mainly with rubella or cytomegalovirus infection. In rubella, the onset is in the second to third decade. It presents with posterior subcapsular cataract, may have iris heterochromia and often develops vitritis without macular oedema. Cytomegalovirus affects predominantly Asian males in the fifth to seventh decade, the keratic precipitates may be pigmented or appear in coin\u2010like pattern or develop nodular endothelial lesions, but rarely vitritis. Eyes with cytomegalovirus tend to have lower endothelial cell counts than the fellow eye. As their ocular manifestations are variable and may overlap considerably, viral AU can pose a diagnostic dilemma. Thus, quantitative polymerase chain reaction or Goldmann\u2010Witmer coefficient assay from aqueous humour samples are preferred to confirm the aetiology and determine the disease severity as this impacts the treatment.<\/jats:p>","DOI":"10.1111\/ceo.13417","type":"journal-article","created":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T05:14:19Z","timestamp":1540185259000},"page":"320-333","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":89,"title":["Demystifying viral anterior uveitis: A review"],"prefix":"10.1111","volume":"47","author":[{"given":"Nicole Shu\u2010Wen","family":"Chan","sequence":"first","affiliation":[{"name":"Singapore National Eye Centre Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6308-5721","authenticated-orcid":false,"given":"Soon\u2010Phaik","family":"Chee","sequence":"additional","affiliation":[{"name":"Singapore National Eye Centre Singapore Singapore"},{"name":"Singapore Eye Research Institute Singapore Singapore"},{"name":"Department of Ophthalmology, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore"},{"name":"Duke\u2010NUS Medical School Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.03.057"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2008.09.001"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2011.363"},{"key":"e_1_2_9_5_1","volume-title":"Ciclite Heterocromica de Fuchs: Ciclite Heterocromica de Fuchs","author":"Monteiro LG","year":"2000"},{"key":"e_1_2_9_6_1","volume-title":"Lehrbuch fu\u00a8r Augenheilkunde","author":"Fuchs E","year":"1926"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1955.00930020181003"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2012.12.008"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2004.02.055"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.06.024"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-010-1434-6"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(00)00409-8"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2004.10.054"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)72322-0"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.03.033"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S60394"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.086546"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/09273948.2017.1394471"},{"key":"e_1_2_9_19_1","doi-asserted-by":"crossref","unstructured":"La HeyE BaarsmaGS De VriesJ KijlstraA.Clinical analysis of Fuchs' heterochromic cyclitis.1991;78:3\u20104.","DOI":"10.1007\/BF00165685"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1991.121"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2005.10.028"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2007.00990.x"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1982.01030040600009"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.1995.tb00661.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"crossref","unstructured":"BasirirB AltanC PinarciEY CelikU SatanaB DemirokA.Analysis of iris structure and iridocorneal angle parameters with anterior segment optical coherence tomography in Fuchs' uveitis syndrome.2013;33:3.","DOI":"10.1007\/s10792-012-9680-8"},{"key":"e_1_2_9_26_1","first-page":"394","article-title":"Fuchs's heterochromic cyclitis: a critical review of the literature. 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