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The disease causes significant morbidity in the population such that patients seek treatment. Multiple clinical studies on pharmacological and mechanical interventions for the treatment of meibomian gland dysfunction have been evaluated. However, there is limited comparative clinical evidence for the effectiveness of these interventions. This review paper aims to report the clinical evidence for pharmaceutical interventions for meibomian gland dysfunction in order to guide clinicians in the management of the disease.<\/jats:p>","DOI":"10.1111\/ceo.13460","type":"journal-article","created":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T08:18:49Z","timestamp":1545121129000},"page":"658-668","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effectiveness of pharmaceutical interventions for meibomian gland dysfunction: An evidence\u2010based review of clinical trials"],"prefix":"10.1111","volume":"47","author":[{"given":"Pauline","family":"Khoo","sequence":"first","affiliation":[{"name":"Save Sight Institute University of Sydney Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth G.\u2010J.","family":"Ooi","sequence":"additional","affiliation":[{"name":"Save Sight Institute University of Sydney Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Watson","sequence":"additional","affiliation":[{"name":"Save Sight Institute University of Sydney Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2,18]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6997b"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200009000-00010"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6997a"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2015-307415"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6703025"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S5555"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ICL.0000060998.20142.8D"},{"key":"e_1_2_7_9_1","volume-title":"External Disease Panel: Preferred Practice Pattern\u00aeGuidelines. 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