{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:28:33Z","timestamp":1784172513024,"version":"3.55.0"},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T00:00:00Z","timestamp":1574812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Importance<\/jats:title><jats:p>Keratoplasty is a surgical procedure to create a more regular optical surface following biomechanical weakening of the cornea in keratoconus. The ideal keratoplasty procedure should also restore corneal biomechanics to that of the healthy cornea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>This study aimed to evaluate and compare the biomechanical properties of corneas following penetrating keratoplasty (PKP) and predescematic deep anterior lamellar keratoplasty (DALK) to those of healthy eyes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective cross\u2010sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Two cohorts of post\u2010keratoplasty eyes (42 eyes with PKP and 27 eyes with DALK) with each other, and with a cohort of 152 healthy eyes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All eyes were examined by slit\u2010lamp biomicroscopy, tomography, anterior segment\u2010OCT and non\u2010contact tonometry CorVis ST (CST).<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>CST biomechanical parameters, maximum corneal deformation (MCD) and corneal energy dissipation were compared between keratoplasty techniques, and with healthy eyes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of participants with PKP and DALK were 35\u2009\u00b1\u200913.7 and 36.1 \u00b1\u200912.6\u2009years, respectively. None of the CST parameters were significantly different between PKP and DALK eyes. However, when compared to healthy corneas, numerous parameters were significantly different for both keratoplasty techniques. Of note, MCD was significantly higher in PKP compared to DALK and healthy corneas, after controlling for co\u2010factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Relevance<\/jats:title><jats:p>Neither type of keratoplasty technique utilized in keratoconus completely restored corneal biomechanical properties to that of healthy corneas. However, PKP resulted in a greater number of parameters significantly different to healthy corneas, compared to DALK.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.13677","type":"journal-article","created":{"date-parts":[[2019,11,9]],"date-time":"2019-11-09T15:28:53Z","timestamp":1573313333000},"page":"174-182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Comparison of corneal biomechanical properties following penetrating keratoplasty and deep anterior lamellar keratoplasty for keratoconus"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1289-3796","authenticated-orcid":false,"given":"Mohammed","family":"Ziaei","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, New Zealand National Eye Centre University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans R.","family":"Vellara","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New Zealand National Eye Centre University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akilesh","family":"Gokul","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New Zealand National Eye Centre University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noor Q.","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New Zealand National Eye Centre University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles N. J.","family":"McGhee","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New Zealand National Eye Centre University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipika V.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, New Zealand National Eye Centre University of Auckland  Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-15123"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cxo.12211"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.13567"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-019-0502-3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(97)00119-7"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-620X.122289"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2015.03.010"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.11.002"},{"key":"e_1_2_6_10_1","first-page":"CD009700","article-title":"Deep anterior lamellar keratoplasty versus penetrating keratoplasty for treating keratoconus","volume":"7","author":"Keane M","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2015-307604"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-014-0344-2"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-925X-13-150"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-13715"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.1145314"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/02713683.2011.556303"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181b81b71"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.83.3.327"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-17396"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-925X-13-55"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181ca6383"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S21297"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01181-6"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.81.3.184"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4835(03)00148-9"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20120518-07"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20130719-06"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/annotation\/1ca782a6-c5c1-4ef8-9c08-ca8ae0cdbaa6"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1968.03850040597020"},{"key":"e_1_2_6_30_1","first-page":"322","article-title":"Corneal wound healing: holographic stress\u2010test analysis","volume":"21","author":"Calkins JL","year":"1981","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4835(82)80053-5"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31823f8ce4"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02697320"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2011.02518.x"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199505000-00010"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.07.090"},{"key":"e_1_2_6_37_1","first-page":"235","article-title":"Ocular biomechanical measurements on post\u2010keratoplasty corneas using a Scheimpflug\u2010based noncontact device","volume":"9","author":"Modis L","year":"2016","journal-title":"Int J Ophthalmol"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001113"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12136"}],"container-title":["Clinical &amp; 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