{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T04:25:35Z","timestamp":1772079935127,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T00:00:00Z","timestamp":1603756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Importance<\/jats:title><jats:p>This is the first comprehensive comparison between ab interno approach and ab externo approach for microcatheter\u2010assisted trabeculotomy in primary congenital glaucoma with clear cornea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Ab externo microcatheter\u2010assisted trabeculotomy is considered to be the gold standard for primary congenital glaucoma. The novel ab interno approach would intuitively be similar to ab externo approach for microcatheter\u2010assisted trabeculotomy in eyes with clear cornea; however, there is no evidence yet.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Non\u2010contemporary comparison of retrospective case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Fifty\u2010eight and fifty\u2010seven consecutive primary congenital glaucoma eyes with clear corneas underwent ab interno and ab externo microcatheter\u2010assisted trabeculotomy, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective comparison of clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Outcome Measures<\/jats:title><jats:p>Surgical success was defined as a postoperative intraocular pressure of \u226421\u2009mmHg with at least a 30% reduction from preoperative IOP with or without the use of anti\u2010glaucoma medication (qualified and complete success, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The qualified success rate (87.9% vs 82.2%, <jats:italic>P<\/jats:italic> =\u2009.40) and complete success rates (81.0% vs 73.3%, <jats:italic>P<\/jats:italic> =\u2009.32) were comparable between groups. Complications were minimal and comparable. Less than 360\u00b0 trabeculotomy (<jats:italic>P<\/jats:italic> =\u2009.009) and a higher number of previous surgeries (<jats:italic>P<\/jats:italic> =\u2009.03) were both associated with worse surgical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Relevance<\/jats:title><jats:p>Ab interno approach provide good and comparable outcomes as ab externo approach for microcatheter\u2010assisted trabeculotomy in primary congenital glaucoma eyes with clear cornea. It should be considered as the initial choice in these patients with the benefit of sparing conjunctiva. Successful trabeculotomy with either technique during the first attempt is critical to overall success and underscores the need for proficiency before independent practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.13868","type":"journal-article","created":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T06:26:16Z","timestamp":1602743176000},"page":"1201-1209","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Ab interno vs ab externo microcatheter\u2010assisted trabeculotomy for primary congenital glaucoma with clear cornea"],"prefix":"10.1111","volume":"48","author":[{"given":"Yan","family":"Shi","sequence":"first","affiliation":[{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital Beijing Institute of Ophthalmology, Capital Medical University  Beijing 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