{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T03:24:23Z","timestamp":1784604263035,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T00:00:00Z","timestamp":1626048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To compare the clinical features and long\u2010term treatment outcomes of patients undergoing secondary intraocular lens (IOL) surgery with scleral\u2010fixated (SFIOL) versus retropupillary iris\u2010claw IOL (RPICIOL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Consecutive patients treated between June 2014 and December 2019 at two tertiary centres were retrospectively reviewed. The primary outcome was the best\u2010corrected visual acuity (BCVA). Secondary outcomes included factors associated with significant corneal endothelial injury and postoperative redislocation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 395 eyes undergoing surgery with SFIOL (237 eyes, 60%) or RPICIOL (158 eyes, 40%), with no differences in baseline BCVA (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.76) or endothelial cell density (ECD) (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.39). Compared with the SFIOL group, the RPICIOL group had faster visual recovery (postoperative month 1, 20\/37 vs. 20\/46, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.005) sustained to over 36\u2009months (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.034), favourable absolute prediction errors (within 0.5D, 67.3% vs. 54.9%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.027), and shorter operation times (52.7 vs. 60.9\u2009min, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.015). There was no difference in ECD after 12\u2009months (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.282). Over a mean follow\u2010up duration of 33\u2009months (152 cases &gt;3\u2009years, 38.5%), the SFIOL group experienced more cases of tilted\/decentred IOLs (14 vs. 1, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.006), suture exposure (7 vs. 0, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.045), and redislocation (17.7% vs. 10.1%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Multivariable regression showed that a final BCVA below 20\/40 was associated with SFIOL (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.007), older age (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.001), intraoperative complications (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.002), past history of vitrectomy\/glaucoma surgery or uveitis (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.046), and surgically induced astigmatism &gt;1D (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.029).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>RPICIOL appears to be a safe and effective surgical option for secondary IOL surgery over a long\u2010term follow\u2010up, comparing favourably against conventional SFIOL.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.13965","type":"journal-article","created":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T15:16:40Z","timestamp":1624979800000},"page":"686-695","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Comparison of long\u2010term surgical outcomes for scleral\u2010fixated versus retropupillary iris\u2010claw intraocular lens"],"prefix":"10.1111","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8359-9618","authenticated-orcid":false,"given":"Hyun Goo","family":"Kang","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul South Korea"},{"name":"Translational Genome Informatics Laboratory, Department of Biomedical Systems Informatics Yonsei University College of Medicine  Seoul South 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Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Severance Eye Hospital Yonsei University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyoung Jun","family":"Koh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Severance Eye Hospital Yonsei University College of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1873-6959","authenticated-orcid":false,"given":"Min","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Institute of Vision Research, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul South 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