{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T22:57:15Z","timestamp":1774479435222,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To report long\u2010term biometric and refractive outcomes in a group of Danish children after surgery for childhood cataract.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Children between 7 and 18\u2009years who had undergone uni\u2010 or bilateral cataract surgery at the Department of Ophthalmology, Rigshospitalet, Denmark, were examined in this cross\u2010sectional study. Swept source optical coherence tomography (OCT) based optical biometry (IOLmaster 700) and anterior tomography (Pentacam) was performed. Healthy fellow eyes from those with unilateral cataract were used as controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 56 children in the study with a median age at surgery of 43.8\u00a0months (1.6\u2013137.6). The amount of higher order aberrations was significantly increased in operated eyes (median root mean square 0.461\u2009\u03bcm [range 0.264\u20131.484]) compared with non\u2010operated eyes (median root mean square 0.337\u2009\u03bcm [range 0.162\u20130.498], <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Younger age at surgery was positively associated with more higher order aberrations at follow\u2010up (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), but we found no significant associations between the amount of higher order aberrations and visual acuity or contrast vision. Longer axial length was associated to glaucoma while shorter axial length was associated to strabismus (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Eyes operated for childhood cataract have higher order aberrations compared with non\u2010operated eyes. Higher order aberrations are complex refractive errors that cannot be corrected by normal lenses and may contribute to poor visual outcomes for the children. We found an association between young age at surgery and higher order aberrations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.14092","type":"journal-article","created":{"date-parts":[[2022,5,7]],"date-time":"2022-05-07T11:08:45Z","timestamp":1651921725000},"page":"590-597","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Biometry and corneal aberrations after cataract surgery in childhood"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7094-7756","authenticated-orcid":false,"given":"Mathias M\u00f8ller","family":"Hansen","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Copenhagen University Hospital \u2010 Rigshospitalet\u2010Glostrup  Glostrup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8249-5104","authenticated-orcid":false,"given":"Daniella","family":"Bach\u2010Holm","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Copenhagen University Hospital \u2010 Rigshospitalet\u2010Glostrup  Glostrup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9375-1510","authenticated-orcid":false,"given":"Line","family":"Kessel","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Copenhagen University Hospital \u2010 Rigshospitalet\u2010Glostrup  Glostrup Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.14081"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01156-7"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/mpa.2002.126492"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2004.06.004"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.01.010"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07\u20100267"},{"issue":"1","key":"e_1_2_7_8_1","first-page":"154","article-title":"Myopia and eye enlargement after neonatal lid fusion in monkeys","volume":"124","author":"Wiesel T","year":"1977","journal-title":"Brain Res"},{"key":"e_1_2_7_9_1","unstructured":"Invest Ophthalmol Vis Sci 1981 20 Emmetropization: a vision\u2010dependent phenomenon"},{"key":"e_1_2_7_10_1","first-page":"1232","article-title":"Increase in axial length of the macaque monkey eye after corneal opacification","volume":"18","author":"Wiesel TN","year":"1979","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_7_11_1","first-page":"750","article-title":"Ocular axial length in unilateral congenital cataracts and blepharoptosis","volume":"28","author":"Noorden GK","year":"1987","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2016.147"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100420.2006.00686.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000516"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.icl.0000195570.73454.a5"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.122.5.695"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874364100802010043"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6702082"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.01.019"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/112067210901900308"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2014.06.016"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417\u2010011\u20101872\u20109"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2005.02.014"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2010.09.019"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2015.07.011.Corneal"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2004.06.068"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2017.03.004"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/266309a0"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.18240\/ijo.2019.05.18"}],"container-title":["Clinical &amp; 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