{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:12:38Z","timestamp":1787314358588,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The aim was to explore the feasibility and safety of performing common surgical steps in epiretinal membrane (ERM) peeling using the Preceyes Surgical System (PSS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a tertiary centre, 15 pseudophakic patients with an idiopathic ERM were randomised to robot\u2010assistance or manual surgery in a 2:1 ratio. In the robot\u2010assisted group, the following steps were performed using PSS: (1) staining the internal limiting membrane (ILM), (2) removal of the dye, (3) creating an ILM flap, (4) completing the peeling, (5) holding a light pipe and (6) fluid\u2013air exchange. Primary outcome measures were feasibility and safety. Secondary outcome measures were duration, best\u2010corrected visual acuity (BCVA) and central retinal thickness (CRT). Moreover, the distance travelled by the instrument during peeling was assessed using motion tracking software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All steps performed with PSS were feasible with no clinical adverse events or complications. The surgical time was longer in the robot\u2010assisted group (mean 56\u2009min, SD\u00a0=\u00a012 vs. 24\u2009min, SD\u00a0=\u00a05). During the study, the duration of robot\u2010assisted surgeries decreased from 72 to 46\u2009min. The distance travelled by the forceps was shorter in the robot\u2010assisted group (mean 403\u2009mm, SD\u00a0=\u00a0186 vs. 550\u2009mm, SD\u00a0=\u00a0134). BCVA and CRT improved equally in both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This is the world's first randomised controlled trial on robotic surgery for ERM. Although more time\u2010consuming, we found that several surgical steps were feasible with assistance of the PSS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ceo.14174","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T05:50:00Z","timestamp":1664517000000},"page":"1057-1064","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Randomised controlled trial on robot\u2010assisted versus manual surgery for pucker peeling"],"prefix":"10.1111","volume":"50","author":[{"given":"Koorosh","family":"Faridpooya","sequence":"first","affiliation":[{"name":"Vitreoretinal Surgery Rotterdam Eye Hospital  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saskia H. M.","family":"van Romunde","sequence":"additional","affiliation":[{"name":"Vitreoretinal Surgery Rotterdam Eye Hospital  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia S.","family":"Manning","sequence":"additional","affiliation":[{"name":"Vitreoretinal Surgery Rotterdam Eye Hospital  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan C.","family":"van Meurs","sequence":"additional","affiliation":[{"name":"Vitreoretinal Surgery Rotterdam Eye Hospital  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerrit J. L.","family":"Naus","sequence":"additional","affiliation":[{"name":"Preceyes BV  Eindhoven The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten J.","family":"Beelen","sequence":"additional","affiliation":[{"name":"Preceyes BV  Eindhoven The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thijs C. M.","family":"Meenink","sequence":"additional","affiliation":[{"name":"Preceyes BV  Eindhoven The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorrit","family":"Smit","sequence":"additional","affiliation":[{"name":"Preceyes BV  Eindhoven The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc D.","family":"de Smet","sequence":"additional","affiliation":[{"name":"Preceyes BV  Eindhoven The Netherlands"},{"name":"Mios Sa  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ases.12087"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4825(94)00042-O"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01880668"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1983.01040010623020"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.157594"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000561"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1167\/tvst.8.3.26"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e318068de46"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000476"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.14003"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-014644"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/939748"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-020-04613-y"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000002720"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-018-0248-4"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-018-6023-5"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e318209b730"},{"key":"e_1_2_7_19_1","volume-title":"Evaluation of OCT Versus Surgeon\u2010Guided Robotic Manipulation in a Simulated Vitreoretinal Model","author":"Romunde S","year":"2018"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.14822"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.09.038"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/10704282_112"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1109\/BIOROB.2010.5625991"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1109\/ROBOT.2007.363056"},{"key":"e_1_2_7_25_1","first-page":"543","article-title":"Cooperative robot assistant for retinal microsurgery","volume":"11","author":"Fleming I","year":"2008","journal-title":"Med Image Comput Comput Assist Interv"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-018-2053-3"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11548-009-0374-2"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-017-3656-3"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2010.193391"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-021-01599-7"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_1131_18"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-017-3763-1"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12830"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2016-309190"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11548-009-0301-6"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11548-018-1829-0"}],"container-title":["Clinical &amp; 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