{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T10:19:33Z","timestamp":1793787573981,"version":"4.6.1"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,6]],"date-time":"2022-11-06T00:00:00Z","timestamp":1667692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1173403"],"award-info":[{"award-number":["APP1173403"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The main objectives of this study were to determine whether known risk factors for trabeculectomy failure similarly influence gelatin stent outcomes and to identify surgical factors which may optimise success.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective, observational study was conducted at a single centre in Perth, Western Australia over 24\u2009months. Two\u2010hundred and sixty\u2010two eyes of 207 patients underwent XEN\u201045 stent surgery with various forms of glaucoma. Surgical and postoperative data on subjects undergoing XEN\u201045 stent surgery was collated. Intraocular pressure (IOP) reduction success was determined using three criteria: 1; IOP &lt;18\u2009mm Hg, 2: IOP &lt;15\u2009mm Hg and 3: &gt;25% IOP reduction from baseline. Kaplan\u2013Meier, mixed effects Cox Proportional hazard model and Chi\u2010Square test were used to measure survival of functioning stents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The success rates at a maximum of 2\u2009years after surgery by criteria 1, 2 and 3 were 61.3%, 26.2% and 28.9% in primary open angle glaucoma (<jats:italic>n<\/jats:italic>\u00a0=\u00a0243), 18.8%, 16.9%, 21.4% in angle closure glaucoma (<jats:italic>n<\/jats:italic>\u00a0=\u00a011), 0%, 0%, 66.7% in congenital glaucoma (<jats:italic>n<\/jats:italic>\u00a0=\u00a05) and 0% in uveitic glaucoma (<jats:italic>n<\/jats:italic>\u00a0=\u00a03). No significant reduction in success was found in those eyes that had prior ocular surgery (all <jats:italic>p<\/jats:italic>\u2009&gt;\u20090.07).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Prior cataract or trabeculectomy surgery does not appear to adversely affect gelatin stent outcomes over 2\u2009years follow up. Gelatin stent surgery appears to have less IOP reduction effect compared to trabeculectomy at 2\u2009years.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.14181","type":"journal-article","created":{"date-parts":[[2022,10,26]],"date-time":"2022-10-26T14:09:15Z","timestamp":1666793355000},"page":"19-30","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Outcomes of 45 \u03bcm gelatin stent surgery over 24\u2010month follow\u2010up"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0723-6334","authenticated-orcid":false,"given":"Aleksandar","family":"Vukmirovic","sequence":"first","affiliation":[{"name":"Lions Eye Institute  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0405-8272","authenticated-orcid":false,"given":"Jessica","family":"Ong","sequence":"additional","affiliation":[{"name":"Lions Eye Institute  Perth Western Australia Australia"},{"name":"Ophthalmology department Royal Perth Hospital  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aqif","family":"Mukhtar","sequence":"additional","affiliation":[{"name":"Lions Eye Institute  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9490-534X","authenticated-orcid":false,"given":"Dao\u2010Yi","family":"Yu","sequence":"additional","affiliation":[{"name":"Lions Eye Institute  Perth Western Australia Australia"},{"name":"Ophthalmology department Royal Perth Hospital  Perth Western Australia Australia"},{"name":"Centre for Ophthalmology and Visual Science University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3722-6922","authenticated-orcid":false,"given":"William H.","family":"Morgan","sequence":"additional","affiliation":[{"name":"Lions Eye Institute  Perth Western Australia Australia"},{"name":"Ophthalmology department Royal Perth Hospital  Perth Western Australia Australia"},{"name":"Centre for Ophthalmology and Visual Science University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2009.06.004"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e3181fe2226"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.09.043"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2006.07.020"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000000493"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.09.014"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3341\/kjo.2011.25.6.401"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2013.5605"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2010.348"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.05.004"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.01.032"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1214\/009053606000000425"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2009.05.032"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000000490"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol\u20102020\u2010317303"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_1328_18"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-9071.2004.00752.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(87)90091-9"},{"key":"e_1_2_7_20_1","first-page":"219","article-title":"Does medical treatment infuence the success of trabeculectomy?","volume":"102","author":"Flach AJ","year":"2004","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2014.0008"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.4.418"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_682_18"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.13463"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-021-02069-5"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6700148"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.05.024"}],"container-title":["Clinical &amp; 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