{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T03:03:05Z","timestamp":1789009385027,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T00:00:00Z","timestamp":1723161600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271119"],"award-info":[{"award-number":["82271119"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To establish a novel vault prediction formula after implantable collamer lens (ICL) implantation that considers both anterior and posterior chamber characteristics with multi\u2010modal parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 103 and 65 eyes were included in the development and validation groups, respectively. Exploratory factor analysis was performed using data from optical coherence tomography and ultrasound biomicroscopy in the development group to synthesise summative factors with different clinical significance. Dominant original metrics with heavy loadings on significant factors (absolute value of the loading coefficient &gt;0.5) were screened for multivariate linear regression models using a stepwise method. The newly derived formula was evaluated and compared to the NK and KS formulas in the validation group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Six factors (anterior chamber angle, horizontal width, lens, iris, iridociliary complex and ciliary body) were generated after dimension reduction via factor analysis. Factors 2 (horizontal width), 3 (lens), and 5 (iridociliary complex) had a significant influence on the vault. When dominant metrics on these factors were screened for further model building, ICL size, anterior chamber width, crystalline lens rise, iris curvature, and iris\u2010ciliary process distance were retained in the final formula, with an adjusted <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> of 0.698, a median absolute error of 81.97\u2009mm, and a root\u2010mean\u2010square error of 103.35\u2009mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Multiple intraocular components, including the lens, iris, and ciliary body, play important roles in vault determination. The new formula exhibits good accuracy for vault predictions and ICL size recommendations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.14433","type":"journal-article","created":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T11:33:40Z","timestamp":1723203220000},"page":"920-933","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Establishment of a new vault prediction formula after implantable collamer lens implantation based on factor analysis of multi\u2010modal ophthalmic parameters of anterior and posterior chamber"],"prefix":"10.1111","volume":"52","author":[{"given":"Yijia","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology and Optometry Eye &amp; ENT Hospital, Fudan University  Shanghai China"},{"name":"NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia Chinese Academy of Medical Sciences  Shanghai China"},{"name":"Shanghai Research Center of Ophthalmology and Optometry  Shanghai China"},{"name":"Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000)  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Optometry Eye &amp; 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