{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T02:47:36Z","timestamp":1777430856926,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Paediatric periorbital cellulitis, a common eye condition, typically requires inpatient admission for intravenous antibiotics due to concerns about orbital spread. This study aimed to assess the safety and effectiveness of ambulatory management for children with moderate periorbital cellulitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Over a 24\u2010month period, we prospectively enrolled 84 children aged 1 to 16\u2009years who presented with moderate periorbital cellulitis to the emergency department. Demographic and clinical data were collected. Following a guideline\u2010based decision tree, eligible children received intravenous antibiotics and were discharged with a peripheral cannula for follow\u2010up in ambulatory care and ophthalmology clinics. Descriptive statistics were used for data presentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 84 children, 62 (73.8%) were managed through the ambulatory care model. Within the category of moderate POC, those who were admitted to the hospital did not have higher CRP or White Cell counts and received IV antibiotics for the same length of time. The ambulatory care clinic provided a total of 132 daily doses of intravenous antibiotics. Two children treated on this pathway required inpatient admission due to clinical deterioration, one of whom required ophthalmic surgical intervention. There was no mortality or sight\u2010threatening complications in this study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Implementing a directed ambulatory care pathway for children with moderate periorbital cellulitis proved to be an effective and safe management strategy. This approach reduces the strain on hospital bed occupancy while promoting community\u2010based patient care.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.14455","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T11:23:18Z","timestamp":1729682598000},"page":"184-193","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of moderate periorbital cellulitis and home\u2010based therapy in children (<scp>EPOCH<\/scp> study, Part 2): A prospective single centre cohort study"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9072-013X","authenticated-orcid":false,"given":"Zachary","family":"McPherson","sequence":"first","affiliation":[{"name":"Emergency Department The Children's Hospital at Westmead  Westmead New South Wales Australia"},{"name":"Faculty of Medicine and Health The University of Sydney  Sydney New South Wales 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