{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:52:19Z","timestamp":1747183939400,"version":"3.40.5"},"reference-count":73,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100019579","name":"SingHealth","doi-asserted-by":"publisher","award":["05\/FY2016\/P2\/20\u2010A47"],"award-info":[{"award-number":["05\/FY2016\/P2\/20\u2010A47"]}],"id":[{"id":"10.13039\/100019579","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To identify the utilisation, type, and psychometric properties of patient\u2010centered outcome measures (PCOMs) associated with the performance\u2010based assessment of visual function (VF) in age\u2010related macular degeneration (AMD) in clinical care and research.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic literature search identified studies, available in English, that used PCOMs to assess VF in patients with any AMD severity, published from January 2015 to November 2023. Two researchers screened studies for quality using the Mixed Methods Appraisal Tool (MMAT) 2018 and assessed the psychometric properties of the PCOMs with the guidance of Consensus\u2010based Standards for the selection of health Measurement Instruments (COSMIN).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 514 studies shortlisted in the literature, 31 were eligible with the majority (77.4%) fulfilling all the MMAT criteria, indicating good quality. The most used PCOM was reading (14\/31\u2009=\u200945.1%), with 5 of the 14 studies (35.7%) showing that the increasing severity and\/or progression of AMD were associated with a worsening reading ability. AMD also negatively affected mobility and physical activity levels (7\/31\u2009=\u200922.6%), and visual search and exploration (4\/31\u2009=\u200912.9%). Based on the COSMIN checklist, apart from reading and physical activity measured with the accelerometer, the other PCOMs had \u2018inadequate\u2019 psychometric properties.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Limited published studies include PCOMs as an assessment of VF in AMD patients. Apart from reading, there is a lack of robust validation data to support the widespread use of other PCOMs. Hence, well\u2010designed, robustly validated, and simple to use PCOMs are required for more widespread implementation in AMD clinical care and research.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ceo.14466","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T04:29:04Z","timestamp":1732249744000},"page":"161-174","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Utilisation of patient\u2010centred outcome measures in age\u2010related macular degeneration research and clinical practice: A systematic review"],"prefix":"10.1111","volume":"53","author":[{"given":"Cheng Yi","family":"Loo","sequence":"first","affiliation":[{"name":"Singapore National Eye Centre  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva K.","family":"Fenwick","sequence":"additional","affiliation":[{"name":"Singapore Eye Research Institute  Singapore"},{"name":"Duke\u2010NUS Medical School  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan E. 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