{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T10:52:16Z","timestamp":1788519136411,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To evaluate changes in OCTA\u2010derived structural and vascular parameters before and after axial length (AL) magnification correction using two different formulas, and to explore their correlations with vessel density (VD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This study included 45 high myopic eyes and 45 age\u2010 and gender\u2010matched controls. Both 6\u2009\u00d7\u20096\u2009mm\n                      <jats:sup>2<\/jats:sup>\n                      optic nerve head imaging and biological measurement were performed using OCTA. Magnification correction was performed using both the Bennett formula and the device's built\u2010in algorithm. Parameters analysed included retinal nerve fibre layer (RNFL) thickness, superficial vascular complex (SVC) VD, deep vascular complex (DVC) VD, and choroidal VD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In long AL eyes, uncorrected values underestimated RNFL thickness and SVC VD but overestimated DVC VD and choroidal VD; discrepancies increased with AL. The opposite pattern was observed in shorter eyes. After correction, all vascular parameters except DVC VD showed significant changes in the high myopia group, while non\u2010high myopic eyes showed no significant differences. The two correction methods showed strong agreement across all layers. RNFL thickness correlated strongly with SVC VD, and choroidal thickness (CT) with choroidal VD, both before and after correction. Post\u2010correction, AL was no longer associated with RNFL thickness or SVC VD, while its correlation with CT and choroidal VD persisted. Mediation analysis showed AL fully mediated the CT\u2013choroidal VD relationship, with a stronger effect post\u2010correction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Magnification correction is crucial in high myopic eyes. Both formulas showed high consistency. Correction eliminated AL's confounding effects on RNFL and SVC VD, while emphasising its mediating role between CT and choroidal VD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ceo.14585","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T07:43:55Z","timestamp":1753170235000},"page":"908-917","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of the Peripapillary Structure\u2013Vessel Density Relationship Before and After Axial Length Magnification Correction Using Different Methods"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-8844-5923","authenticated-orcid":false,"given":"Zhuoyan","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Ophthalmology The Second Affiliated Hospital of Xi'an Jiaotong University  Xi'an Shaanxi Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yidan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology The Second Affiliated Hospital of Xi'an Jiaotong University  Xi'an Shaanxi Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxin","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology The Second Affiliated Hospital of Xi'an Jiaotong University  Xi'an Shaanxi Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyuan","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology The Second Affiliated Hospital of Xi'an Jiaotong University  Xi'an Shaanxi Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianming","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology The Second Affiliated Hospital of Xi'an Jiaotong University  Xi'an Shaanxi Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruihua","family":"Jing","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology The Second Affiliated Hospital of Xi'an Jiaotong University  Xi'an Shaanxi Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo-2021-321025"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.1033838"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.62.10.15"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000531509"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.65.12.2"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-71388-1"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2019.4821"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1475-1313.2003.00140.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xops.2022.100134"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.17-21551"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.06-1315"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.17-22865"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2020-316222"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2016.07.006"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00175988"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-69864-9"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.51.2.115"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1990.39"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000001671"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.21037\/qims-20-1011"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-019-1177-z"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-4737"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-017-0544-0"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2020.102008"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2018.01.026"},{"key":"e_1_2_7_27_1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179320","article-title":"Age and Axial Length on Peripapillary Retinal Nerve Fiber Layer Thickness Measured by Optical Coherence Tomography in Nonglaucomatous Taiwanese Participants","volume":"12","author":"Bhattacharya S.","year":"2017","journal-title":"PLoS One"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2018.05.022"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-010791"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-8214"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2020.100933"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.900486"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.64.7.7"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40662-021-00269-9"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1241352"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.3109\/02713689308999467"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-21289"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-024-06403-2"}],"container-title":["Clinical &amp; Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ceo.14585","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T04:26:26Z","timestamp":1762662386000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ceo.14585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,22]]},"references-count":37,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/ceo.14585"],"URL":"https:\/\/doi.org\/10.1111\/ceo.14585","archive":["Portico"],"relation":{},"ISSN":["1442-6404","1442-9071"],"issn-type":[{"value":"1442-6404","type":"print"},{"value":"1442-9071","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,22]]},"assertion":[{"value":"2025-05-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}