{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:48:03Z","timestamp":1787726883140,"version":"build-2784847793"},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T00:00:00Z","timestamp":1753228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Exper Ophthalmology"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To evaluate the association between prior selective laser trabeculoplasty (SLT) on intraocular pressure (IOP) lowering efficacy of phacoemulsification combined with iStent inject (phaco\u2010iStent).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective study of 1550 eyes of 1023 patients with and without prior SLT that underwent phaco\u2010iStent. Surgical success was defined at 12\u2009months using three different endpoints: (A) IOP \u2264\u200921\u2009mmHg and \u2265\u200920% IOP decrease, or\u2009\u2265\u20091 medication reduction vs. baseline, (B)\u2009\u2265\u20091 medication reduction with no increase in baseline IOP or (C) IOP \u2264\u200921\u2009mmHg and \u2265\u200920% IOP decrease alone with no increase in baseline medication use. The prior SLT and no SLT patients were propensity score matched by age, baseline IOP and IOP\u2010lowering medication use and visual field mean deviation (VF MD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Three hundred and sixty\u2010eight eyes (184 eyes per group) of 313 patients were matched based on baseline IOP and medications, VF MD, and age at surgery. Prior SLT was associated with an increased risk of failure using endpoints A [hazards ratio (HR) 2.13, 95% confidence intervals (CI) 1.34\u20143.38], B (HR 1.73, CI 1.1\u20142.72) and C (HR 1.51, CI 1.05\u20142.16). In eyes with prior SLT, higher baseline IOP was significantly associated with a lower risk of failure to achieve a minimum 20% reduction in IOP from baseline (HR 0.89, 0.85\u20140.94,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this observational study, prior SLT was associated with an increased risk of failure after phaco\u2010iStent inject surgery. In eyes with prior SLT, there was a significantly decreased risk of failure in eyes with higher baseline IOP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ceo.14588","type":"journal-article","created":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T07:23:18Z","timestamp":1753255398000},"page":"1148-1155","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Association Between Prior Selective Laser Trabeculoplasty and Phaco\u2010\n                    <scp>iStent<\/scp>\n                    Inject Efficacy"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4117-7446","authenticated-orcid":false,"given":"Jeremy C. K.","family":"Tan","sequence":"first","affiliation":[{"name":"Save Sight Institute, Faculty of Medicine and Health, University of Sydney  Sydney New South Wales Australia"},{"name":"Department of Ophthalmology Prince of Wales Hospital  Randwick New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1484-2615","authenticated-orcid":false,"given":"Colin I.","family":"Clement","sequence":"additional","affiliation":[{"name":"Save Sight Institute, Faculty of Medicine and Health, University of Sydney  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"White","sequence":"additional","affiliation":[{"name":"Centre for Vision Research, Westmead Institute for Medical Research  Westmead New South Wales 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